Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Division of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
MAGMA. 2020 Apr;33(2):293-298. doi: 10.1007/s10334-019-00776-w. Epub 2019 Sep 24.
It is necessary to standardize the examination procedure and diagnostic criteria of diffusion tensor imaging (DTI). Thus, the purpose of this study was to examine the reproducibility of measurements using a standardization phantom composed of different fibre materials with different fibre densities (FDs) for the evaluation of fractional anisotropy (FA) derived from DTI.
Two types of fibre materials wrapped in heat-shrinkable tubes were used as fibre phantoms. We designed fibre phantoms with three different FDs of each fibre material. The standardization phantom was examined using DTI protocol six times a day, and each examination session was repeated once a month for 7 consecutive months. Fibre tracking was performed by setting regions of interest in the FA map, and FA was measured in each fibre phantom. Coefficients of variation (CVs) were used to evaluate the inter-examination reproducibility of FA values. Furthermore, Bland-Altman plots were used to evaluate the intra-operator reproducibility of FA measurements.
All CVs for each fibre phantom were within 2% throughout the 7-month study of repeated DTI sessions. The high intra-operator reproducibility of the FA measurement was confirmed.
High reproducibility of measurements using a standardization phantom for the evaluation of FA was achieved.
有必要对弥散张量成像（DTI）的检查程序和诊断标准进行标准化。因此，本研究旨在通过使用由不同纤维密度（FD）的不同纤维材料组成的标准化体模来检查基于 DTI 得出的各向异性分数（FA）测量的可重复性。
两种类型的纤维材料用热缩管包裹作为纤维体模。我们设计了每种纤维材料具有三种不同 FD 的纤维体模。使用 DTI 方案每天检查标准化体模六次，每个检查阶段每月重复一次，共连续 7 个月。通过在 FA 图中设置感兴趣区域来进行纤维追踪，并在每个纤维体模中测量 FA。变异系数（CV）用于评估 FA 值的检查间可重复性。此外，Bland-Altman 图用于评估 FA 测量的操作者内可重复性。
在重复 DTI 检查的 7 个月期间，每个纤维体模的所有 CV 均在 2%以内。FA 测量的高操作者内可重复性得到了确认。
通过使用用于评估 FA 的标准化体模实现了测量的高重复性。
