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影响转流造口关闭发病率和死亡率的因素:十二年回顾性队列分析

Factors affecting the morbidity and mortality of diverting stoma closure: retrospective cohort analysis of twelve-year period.

作者信息

Krebs Bojan, Ivanecz Arpad, Potrc Stojan, Horvat Matjaz

机构信息

Department for Abdominal Surgery, University Clinical Centre Maribor, Maribor Slovenia.

出版信息

Radiol Oncol. 2019 Sep 24;53(3):331-336. doi: 10.2478/raon-2019-0037.

Abstract

Background Diverting stoma is often performed in rectal cancer surgery for reducing the consequences of possible anastomotic failure. Closing of stoma follows in most cases after a few months. The aim of our study was to evaluate morbidity and mortality after diverting stoma closure and to identify risk factors for complications of this procedure. Patients and methods At our department, we have performed a retrospective cohort analysis of data for 260 patients with diverting stoma closure from 2003 to 2015. Age, stoma type, patient's preoperative ASA score, surgical technique and time to stoma closure were investigated as factors which could influence the complication rate. Results 218 patients were eligible for investigation. Postoperative complications developed in 54 patients (24.8%). Most common complications were postoperative ileus (10%) and wound infection (5%). Four patients died (1.8%). There was no effect on complication rate regarding type of stoma, closing technique, patient's ASA status and patient age. The only factor influencing the complication rate was the time to stoma closure. We found that patients which had the stoma closed prior to 8 months after primary surgery had lower overall complication rate (p<0. 05). Conclusions To reduce overall complication rate, our data suggest a shorter period than 8 months after primary surgery before closure of diverting stoma. As diverting stoma closure is not a simple operation, all strategies should be taken to reduce significant morbidity and mortality rate.

摘要

背景

直肠癌手术中常采用造口术以减轻可能出现的吻合口漏的后果。多数情况下,造口会在数月后关闭。本研究旨在评估造口关闭术后的发病率和死亡率,并确定该手术并发症的危险因素。

患者与方法

我们科室对2003年至2015年间260例行造口关闭术的患者数据进行了回顾性队列分析。研究了年龄、造口类型、患者术前ASA评分、手术技术以及造口关闭时间等可能影响并发症发生率的因素。

结果

218例患者符合研究条件。54例患者(24.8%)出现术后并发症。最常见的并发症是术后肠梗阻(10%)和伤口感染(5%)。4例患者死亡(1.8%)。造口类型、关闭技术、患者ASA状态和患者年龄对并发症发生率均无影响。唯一影响并发症发生率的因素是造口关闭时间。我们发现,初次手术后8个月内关闭造口的患者总体并发症发生率较低(p<0.05)。

结论

为降低总体并发症发生率,我们的数据表明,初次手术后造口关闭时间应短于8个月。由于造口关闭术并非简单手术,应采取一切策略降低显著的发病率和死亡率。

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