Otorhinolaryngology Department, Acibadem University Atakent Hospital, Istanbul, Turkey.
Otorhinolaryngology Department, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey.
Eur Arch Otorhinolaryngol. 2020 Jan;277(1):141-145. doi: 10.1007/s00405-019-05659-3. Epub 2019 Sep 25.
Many studies have investigated the effect of Helicobacter pylori (H. pylori) colonization on the development of allergic diseases, but with conflicting results. The purpose of this cross-sectional observation study is to estimate H. pylori prevalence in allergic and nonallergic nasal conditions and compare with normal population.
274 patients were tested for H. pylori with stool antigen test. Patients were compared with the control group for H. pylori positivity rates after they were categorized according to their primary diagnoses as mite allergy, pollen allergy, mite and pollen allergy, and non-allergic rhinitis with eosinophilic syndrome (NARES). Results were also classified according to age.
The number of H. pylori-positive patients with mite allergy, mite and pollen allergy, and NARES were significantly higher than the control group in sadults. The percentages of patients in the pediatric group who had mite allergy, pollen allergy, mite and pollen allergy, or NARES were not significantly different when compared to the control group.
Forthcoming studies would undoubtedly evaluate of the profits of treating allergic nasal conditions by treating the aforementioned bacterial infection.
许多研究已经调查了幽门螺杆菌(H. pylori)定植对过敏性疾病发展的影响,但结果存在矛盾。本横断面观察性研究的目的是估计过敏性和非过敏性鼻部疾病中 H. pylori 的流行率,并与正常人群进行比较。
对 274 例患者进行粪便抗原检测以检测 H. pylori。根据主要诊断将患者分为螨过敏、花粉过敏、螨和花粉过敏以及非变应性鼻炎伴嗜酸性粒细胞增多综合征(NARES),然后将患者与对照组进行 H. pylori 阳性率比较。结果还根据年龄进行了分类。
成人螨过敏、螨和花粉过敏以及 NARES 患者中 H. pylori 阳性患者的数量明显高于对照组。与对照组相比,儿科组中患有螨过敏、花粉过敏、螨和花粉过敏或 NARES 的患者百分比没有显着差异。
未来的研究无疑将评估通过治疗上述细菌感染来治疗过敏性鼻部疾病的获益。