Gallardo Diego I, Gómez Yolanda M, Gómez Héctor W, de Castro Mário
Departamento de Matemática, Facultad de Ingeniería, Universidad de Atacama, Chile.
Departamento de Matemáticas, Facultad de Ciencias Básicas, Universidad de Antofagasta, Chile.
Stat Methods Med Res. 2020 Jul;29(7):1831-1845. doi: 10.1177/0962280219876962. Epub 2019 Sep 27.
In this paper, we propose a generalization of the power series cure rate model for the number of competing causes related to the occurrence of the event of interest. The model includes distributions not yet used in the cure rate models context, such as the Borel, Haight and Restricted Generalized Poisson distributions. The model is conveniently parameterized in terms of the cure rate. Maximum likelihood estimation based on the Expectation Maximization algorithm is discussed. A simulation study designed to assess some properties of the estimators is carried out, showing the good performance of the proposed estimation procedure in finite samples. Finally, an application to a bone marrow transplant data set is presented.
在本文中,我们针对与感兴趣事件发生相关的竞争原因数量,提出了幂级数治愈率模型的一种推广。该模型包含了尚未在治愈率模型背景中使用的分布,如博雷尔分布、海特分布和受限广义泊松分布。该模型以治愈率进行了方便的参数化。讨论了基于期望最大化算法的最大似然估计。开展了一项旨在评估估计量某些性质的模拟研究,结果表明所提出的估计程序在有限样本中具有良好的性能。最后,给出了对一个骨髓移植数据集的应用。