University of Rochester, Medical Center, Rochester, New York, USA.
Stanford University Medical Center, Stanford, California, USA.
Gastrointest Endosc. 2019 Dec;90(6):863-876.e33. doi: 10.1016/j.gie.2019.07.033. Epub 2019 Sep 25.
Colonoscopy is the most commonly performed endoscopic procedure and overall is considered a low-risk procedure. However, adverse events (AEs) related to this routinely performed procedure for screening, diagnostic, or therapeutic purposes are an important clinical consideration. The purpose of this document from the American Society for Gastrointestinal Endoscopy's Standards of Practice Committee is to provide an update on estimates of AEs related to colonoscopy in an evidence-based fashion. A systematic review and meta-analysis of population-based studies was conducted for the 3 most common and important serious AEs (bleeding, perforation, and mortality). In addition, this document includes an updated systematic review and meta-analysis of serious AEs (bleeding and perforation) related to EMR and endoscopic submucosal dissection for large colon polyps. Finally, a narrative review of other colonoscopy-related serious AEs and those related to specific colonic interventions is included.
结肠镜检查是最常进行的内镜检查程序，总体上被认为是一种低风险的程序。然而，与该程序的筛查、诊断或治疗目的相关的不良事件（AE）是一个重要的临床考虑因素。美国胃肠内镜学会实践标准委员会这份文件的目的是提供基于证据的结肠镜检查相关 AE 估计的最新信息。对基于人群的研究中最常见和最重要的 3 种严重 AE（出血、穿孔和死亡率）进行了系统回顾和荟萃分析。此外，本文件还包括对与大肠息肉的 EMR 和内镜黏膜下剥离相关的严重 AE（出血和穿孔）的更新系统回顾和荟萃分析。最后，还包括对其他与结肠镜检查相关的严重 AE 以及与特定结直肠干预相关的 AE 的叙述性综述。
