Department of Exercise Sciences, Brigham Young University, Provo, UT.
Department of Statistics, Brigham Young University, Provo, UT.
Med Sci Sports Exerc. 2020 Mar;52(3):746-753. doi: 10.1249/MSS.0000000000002156.
This study investigated the relationship between blood flow restriction (BFR) cuff pressure and blood flow at rest and during exercise, with the aim of determining if lower cuff pressures will provide an ischemic stimulus comparable to higher pressures.
The relationship between blood flow and cuff pressure at rest was determined by measuring blood flow (Doppler Ultrasound) through the superficial femoral artery (SFA) in 23 adults across a range of pressures (0%-100% Arterial Occlusion Pressure at rest [rAOP]). The interplay between cuff pressure, blood flow and exercise was assessed by determining AOP at rest and during plantar flexion exercise (eAOP) and subsequently measuring the blood flow response to plantar flexion exercise with BFR cuff pressure set to either 40% rAOP or 40% eAOP.
At rest, a nonlinear relationship between cuff pressure and blood flow through the SFA exhibited a plateau at moderate pressures, with nonsignificant differences in blood flow (~9%, P = 1.0) appearing between pressures ranging from 40% to 80% rAOP. While eAOP was greater than rAOP (229 ± 1.5 mm Hg vs 202 ± 1.5 mm Hg, P < 0.01), blood flow during plantar flexion exercise did not significantly differ (P = 0.49) when applying 40% rAOP or 40% eAOP.
Blood flow through the SFA exhibits a nonlinear relationship with cuff pressure, such that cuff pressures in the range of 40% to 80% rAOP reduce blood flow to approximately the same degree. The BFR interventions opting for lower (e.g., 40% AOP), more comfortable pressures will likely provide an ischemic stimulus comparable to that of higher (80% AOP), less-comfortable pressures.
本研究旨在探讨血流限制（BFR）袖带压力与休息和运动时血流之间的关系，以确定较低的袖带压力是否会提供与较高压力相当的缺血性刺激。
通过测量 23 名成年人在休息时通过股浅动脉（SFA）的血流（多普勒超声），确定血流与袖带压力在休息时的关系，袖带压力范围为动脉闭塞压的 0%-100%（rAOP）。通过确定休息时的 AOP（rAOP）和跖屈运动时的 AOP（eAOP），并随后用 BFR 袖带压力设定为 40% rAOP 或 40% eAOP 来测量跖屈运动时的血流反应，评估袖带压力、血流和运动之间的相互作用。
在休息时，SFA 血流与袖带压力之间存在非线性关系，在中等压力下出现平台，在 rAOP 范围为 40%-80%时，血流差异无统计学意义（~9%，P = 1.0）。虽然 eAOP 大于 rAOP（229 ± 1.5 mm Hg 比 202 ± 1.5 mm Hg，P < 0.01），但当施加 40% rAOP 或 40% eAOP 时，跖屈运动时的血流无显著差异（P = 0.49）。
SFA 血流与袖带压力呈非线性关系，rAOP 范围为 40%-80%的袖带压力会将血流降低到大致相同的程度。选择较低（例如，40%AOP）、更舒适的压力的 BFR 干预措施可能会提供与较高（80%AOP）、不太舒适的压力相当的缺血性刺激。
