Trybulski Robert, Muracki Jarosław, Wilk Michał, Lupu Gabriel Stanica, Fostiak Krzysztof, Stanula Arkadiusz
Medical Department, Wojciech Korfanty Upper Silesian Academy, 40-659, Katowice, Poland.
Provita Medical Center, 44-240, Żory, Poland.
Eur J Appl Physiol. 2025 Sep 2. doi: 10.1007/s00421-025-05952-6.
Aim was to investigate relationship of gender and training experience with post-occlusive hyperemia (PORH) and answer how differences between men and women and their training status led to differences in vascular responses after occlusions.
This prospective experimental study included 80 healthy volunteers divided into four groups of 20: trained men, trained women, non-training women, and non-training men. The occlusion intervention on the dominant thigh was performed. The laser Doppler flowmetry was used to assess post-occlusion responses by measuring: arterial occlusion pressure-AOPmin[mmHg], total arterial occlusion pressure-AOP100%[mmHg], resting flow-RF[PU], time to peak-TP[s], recovery time-TR[min], and biological zero-BZ[PU].
Men recovered faster than women in trained and untrained groups and showed higher AOPmin, and AOP100% compared to women in both trained and untrained groups. Women had higher RF comparing to men in both trained and untrained groups, and higher BZ but only in the untrained group. Trained people had higher RF, AOPmin and recovered faster to baseline, but had lower TP than non-trained. Trained men had higher AOP100% than untrained men; in women, it was non-significant. There were no significant differences between genders in TP in both trained and untrained subgroups, and in BZ in trained subgroups.
There are significant differences between trained and untrained men and women in microcirculatory parameters after occlusion intervention. Between gender differences were noted only in some parameters which underscores the need of further research.
旨在研究性别和训练经历与闭塞后充血（PORH）之间的关系，并回答男性和女性及其训练状态的差异如何导致闭塞后血管反应的差异。
这项前瞻性实验研究纳入了80名健康志愿者，分为四组，每组20人：受过训练的男性、受过训练的女性、未训练的女性和未训练的男性。对优势大腿进行闭塞干预。使用激光多普勒血流仪通过测量以下指标来评估闭塞后的反应：动脉闭塞压力-AOPmin[mmHg]、总动脉闭塞压力-AOP100%[mmHg]、静息血流-RF[PU]、达到峰值的时间-TP[s]、恢复时间-TR[min]和生物学零值-BZ[PU]。
在受过训练和未受过训练的组中，男性恢复得比女性快，并且在受过训练和未受过训练的组中，男性的AOPmin和AOP100%均高于女性。在受过训练和未受过训练的组中，女性的RF均高于男性，且在未训练组中女性的BZ更高。受过训练的人RF、AOPmin更高，恢复到基线的速度更快，但TP比未受过训练的人低。受过训练的男性的AOP100%高于未受过训练的男性；在女性中，差异不显著。在受过训练和未受过训练的亚组中，TP在性别之间无显著差异，在受过训练的亚组中，BZ在性别之间也无显著差异。
在闭塞干预后，受过训练和未受过训练的男性和女性在微循环参数方面存在显著差异。仅在某些参数中发现了性别差异，这突出了进一步研究的必要性。
