O'Loughlin E V, Robson L, Scott B, Alexander F, Gall D G
J Pediatr Gastroenterol Nutr. 1985 Feb;4(1):135-9. doi: 10.1097/00005176-198502000-00024.
A 12-year-old girl presented with concurrent onset of membranous glomerulonephritis and Crohn's disease of the small intestine. Subsequent investigations failed to implicate any other systemic disease as a cause of the glomerulonephritis. Membranous glomerulonephritis is an immune complex--mediated glomerulopathy frequently associated with underlying systemic disease. The association of immune complex phenomenon with Crohn's disease and the variation of renal abnormalities in parallel with activity of bowel disease in this patient suggest that the glomerulonephritis may be due to the underlying Crohn's disease.
一名12岁女孩同时出现膜性肾小球肾炎和小肠克罗恩病。后续检查未发现任何其他全身性疾病是导致肾小球肾炎的原因。膜性肾小球肾炎是一种免疫复合物介导的肾小球病，常与潜在的全身性疾病相关。该患者免疫复合物现象与克罗恩病相关，且肾脏异常随肠道疾病活动而变化，这表明肾小球肾炎可能归因于潜在的克罗恩病。
