骨髓：能量耗竭时的免疫代谢避难所。
Bone Marrow: An Immunometabolic Refuge during Energy Depletion.
机构信息
Department of Comparative Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Department of Comparative Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT 06520, USA.
出版信息
Cell Metab. 2019 Oct 1;30(4):621-623. doi: 10.1016/j.cmet.2019.08.022.
An integrated immunometabolic response during negative energy balance is required for host survival. Three new papers by Jordan et al. (2019), Nagai et al. (2019), and Collins et al. (2019) report that monocytes, naive B cells, and memory CD8 T cells use bone marrow as a haven to tide off periods of metabolic adversity to maintain immune-responsiveness.
在负能量平衡期间，需要一个综合的免疫代谢反应来维持宿主的生存。Jordan 等人（2019 年）、Nagai 等人（2019 年）和 Collins 等人（2019 年）的三篇新论文报告称，单核细胞、幼稚 B 细胞和记忆 CD8 T 细胞利用骨髓作为避难所，度过代谢逆境期，以维持免疫应答能力。
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