Division of Dermatology, Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy -
Division of Dermatology, Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy.
G Ital Dermatol Venereol. 2019 Dec;154(6):609-623. doi: 10.23736/S0392-0488.19.06458-7. Epub 2019 Sep 26.
Alopecia areata (AA) is an organ-specific autoimmune disorder that targets anagen phase hair follicles. The course is unpredictable and current available treatments have variable efficacy. Nowadays, there is relatively little evidence on treatment of AA from well-designed clinical trials. Moreover, none of the treatments or devices commonly used to treat AA are specifically approved by the Food and Drug Administration. The Italian Study Group for Cutaneous Annexial Disease of the Italian Society of dermatology proposes these Italian guidelines for diagnosis and treatment of Alopecia Areata deeming useful for the daily management of the disease. This article summarizes evidence-based treatment associated with expert-based recommendations.
斑秃(AA)是一种器官特异性自身免疫性疾病,靶向生长期毛囊。病程不可预测,目前可用的治疗方法疗效不一。目前,来自精心设计的临床试验的关于 AA 治疗的证据相对较少。此外,常用于治疗 AA 的治疗方法或设备均未获得美国食品药品监督管理局的专门批准。意大利皮肤病学会皮肤附属器疾病研究组提出了这些意大利斑秃诊断和治疗指南,认为这些指南有助于斑秃的日常管理。本文总结了基于证据的治疗方法和基于专家建议的推荐意见。