Meshram Girish Gulab, Kaur Neeraj, Hura Kanwaljeet Singh
Department of Pharmacology, Postgraduate Institute of Medical Education and Research and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Department of Radiology, University of Texas Health Science Centre, San Antonio, Texas, USA.
Clin Pract. 2019 Sep 17;9(3):1111. doi: 10.4081/cp.2019.1111. eCollection 2019 Aug 2.
Ewing's sarcoma is an aggressive fatal malignancy of bones and soft-tissue. It predominantly affects the young population, with a worldwide incidence of three cases per million. The pelvis, extremities, and ribs are the most common sites. We present a case of massive Ewing's sarcoma of the right femur with metastasis to bones and lungs. The patient was treated with chemotherapy. However, he succumbed to his illness before completion of therapy. In conclusion, Ewing's sarcoma with distant metastasis is a high risk case with poor prognosis. Integrating novel molecular targets with conventional chemotherapeutic agents holds a promise for high-risk Ewing's sarcoma patients.
尤因肉瘤是一种侵袭性的致命性骨与软组织恶性肿瘤。它主要影响年轻人群，全球发病率为每百万人中有三例。骨盆、四肢和肋骨是最常见的发病部位。我们报告一例右股骨巨大尤因肉瘤伴骨与肺转移的病例。该患者接受了化疗。然而，他在治疗完成前因病死亡。总之，伴有远处转移的尤因肉瘤是一种高危病例，预后较差。将新型分子靶点与传统化疗药物相结合有望为高危尤因肉瘤患者带来希望。
