Center for Plastic Surgery and Lasers in Surgery and Medicine, Plastische Chirurgie und Laserzentrum Innsbruck, Innsbruck, 6020, Austria.
Department of Plastic and Reconstructive Surgery, Hospital of the Barmherzige Brüder, Teaching Hospital of the Paracelsus Medical University Salzburg, 5020, Salzburg, Austria.
Lasers Surg Med. 2020 Jan;52(1):77-83. doi: 10.1002/lsm.23160. Epub 2019 Oct 3.
Laser hair removal is the most common laser therapy and the third most commonly performed procedure with more than one million treatments in United States in 2016. This retrospective study was conducted to assess long-term efficacy and safety of the 755 nm laser for hair removal.
STUDY DESIGN/MATERIALS AND METHODS: Nearly, 3,606 laser treatments were performed with the long-pulsed 755 nm wavelength laser equipped with an epidermal cooling device between 1997 and 2005 and were followed till 2013. Standardized assessments were conducted by two treating physicians and patients at two follow-up intervals. At first follow-up, clearance was assessed by two physicians and clearance and satisfaction by patients. At the second follow-up, patients were assessed if hair clearance sustained compared with the first follow-up.
Nine hundred and forty-eight patients with Fitzpatrick skin types I-IV were treated with a total of 3,606 laser treatments in this study. The mean age at the beginning of the study was 35 years (±11), 95.1% of patients were female (n = 902) and 4.9% male (n = 46). Five hundred and seventy-four patients received a minimum of three treatments and an average of 5.31 (3-16) treatments on axilla, back, bikini, breast, abdomen, face, lower extremity, or upper extremity region. First, follow-up was conducted 3.9 (±1.5) years after the final laser treatment. Seventy-four percent of these patients received 75-100% clearance as reported by the physician and 48% clearance as reported by the patient. Fifty-two percent of patients reported slower hair growth and 42% change in hair texture. Ninety percent of patients treated on axilla, 82% treated on the bikini area, and 79% treated on lower extremities experienced 75% or more clearance after three treatments. Facial, as well as breast and abdomen treatments, only showed a 66% and 62%, respectively, after three treatments. For these locations, five and more treatments were needed to achieve a quote of 79% (face) or 80% (breast and abdomen) for a 75-100% clearance. Upper extremity and back treatments did not have enough physician ratings to draw conclusions. Long-term adverse events were minimal and were all located on the face (one patient scar, four patients herpes infection). Second follow-up of 173 patients was conducted after 11.5 years (±2.0) and 87.9% of patients reported that their improvement sustained.
The long-pulsed 755 nm alexandrite laser is a safe and efficacious treatment for the reduction of unwanted body hair with permanent results and high patient satisfaction. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.
激光脱毛是最常见的激光治疗方法，也是美国 2016 年进行的第三大常见程序，超过 100 万次治疗。本回顾性研究旨在评估长脉冲 755nm 激光脱毛的长期疗效和安全性。
研究设计/材料和方法：1997 年至 2005 年间，使用长脉冲 755nm 波长激光（配备表皮冷却装置）进行了近 3606 次激光治疗，并随访至 2013 年。两名治疗医生和患者在两个随访间隔进行了标准化评估。第一次随访时，由两名医生评估清除情况，由患者评估清除情况和满意度。在第二次随访中，如果与第一次随访相比头发仍保持清除，则评估患者的情况。
本研究共治疗了 948 名 Fitzpatrick 皮肤类型 I-IV 的患者，共进行了 3606 次激光治疗。研究开始时的平均年龄为 35 岁（±11），95.1%的患者为女性（n=902），4.9%为男性（n=46）。574 名患者至少接受了 3 次治疗，平均在腋窝、背部、比基尼区、乳房、腹部、面部、下肢或上肢区域接受 5.31（3-16）次治疗。第一次随访在最后一次激光治疗后 3.9（±1.5）年进行。这些患者中有 74%的患者报告医生报告的清除率为 75-100%，48%的患者报告患者报告的清除率为 75-100%。52%的患者报告毛发生长缓慢，42%的患者报告毛发质地改变。90%接受腋窝治疗、82%接受比基尼区治疗、79%接受下肢治疗的患者在接受 3 次治疗后清除率达到 75%或更高。面部、乳房和腹部治疗仅在 3 次治疗后显示 66%和 62%的清除率。对于这些部位，需要 5 次或更多次治疗才能达到 79%（面部）或 80%（乳房和腹部）的 75-100%清除率。上肢和背部治疗没有足够的医生评估来得出结论。长期不良事件很少见，均位于面部（1 例患者出现瘢痕，4 例患者出现疱疹感染）。对 173 名患者进行了 11.5 年（±2.0）的第二次随访，87.9%的患者报告他们的改善持续存在。
长脉冲 755nm 亚历山大激光是一种安全有效的减少身体多余毛发的治疗方法，具有永久性效果和高患者满意度。激光外科学杂志。© 2019 年 Wiley 期刊，Inc.
