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富含亮氨酸的乳清蛋白补充剂对参加 12 周抗阻训练计划的住院后老年人体能的影响:一项随机对照试验。

Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial.

机构信息

Department of Pharmacy and Food Science, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.

Department of Medicine, Araba University Hospital, Bioaraba Research Institute, OSI Araba. CIBERSAM, University of the Basque Country (UPV/EHU), 01004 Vitoria-Gasteiz, Spain.

出版信息

Nutrients. 2019 Oct 1;11(10):2337. doi: 10.3390/nu11102337.

DOI:10.3390/nu11102337
PMID:31581591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6835698/
Abstract

Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein supplement is not so clear. The aim of this study was to examine the effect of a whey protein supplement enriched with leucine after resistance training on muscle mass and strength gains in a post-hospitalized elderly population. A total of 28 participants were included and allocated to either protein supplementation or placebo supplementation following resistance training for 12 weeks (2 days/week). Physical function (lower and upper body strength, aerobic capacity and the Short Physical Performance Battery (SPPB) test), mini nutritional assessment (MNA) and body composition (Dual X-ray Absorptiometry) were assessed at baseline and after 12 weeks of resistance training. Both groups showed improvements in physical function after the intervention ( < 0.01), but there were no further effects for the protein group ( > 0.05). Muscle mass did not improve after resistance training in either group ( > 0.05). In conclusion, 12 weeks of resistance training are enough to improve physical function in a post-hospitalized elderly population with no further benefits for the protein-supplemented group.

摘要

随着急性活动期的结束,年龄相关的力量和肌肉质量损失会进一步增加。为了避免这种情况,抗阻训练已被提议作为一种有效的对策,但蛋白质补充的额外效果并不那么明确。本研究的目的是检验在抗阻训练后补充富含亮氨酸的乳清蛋白对住院后老年人群的肌肉质量和力量增加的影响。共有 28 名参与者被纳入研究,并在抗阻训练 12 周(每周 2 天)后被分配到蛋白质补充组或安慰剂补充组。在基线和抗阻训练 12 周后评估身体功能(下肢和上肢力量、有氧能力和简易体能状况量表(SPPB)测试)、微型营养评估(MNA)和身体成分(双能 X 线吸收法)。两组在干预后均改善了身体功能( < 0.01),但蛋白质组没有进一步的效果( > 0.05)。两组的肌肉质量在抗阻训练后均未改善( > 0.05)。总之,12 周的抗阻训练足以改善住院后老年人群的身体功能,而补充蛋白质对补充组没有进一步的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f2/6835698/2165d39e80b8/nutrients-11-02337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f2/6835698/2165d39e80b8/nutrients-11-02337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f2/6835698/2165d39e80b8/nutrients-11-02337-g001.jpg

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