Kopelman H A, Forman M B, Wilson B H, Kolodgie F D, Smith R F, Friesinger G C, Virmani R
J Am Coll Cardiol. 1985 Jun;5(6):1302-7. doi: 10.1016/s0735-1097(85)80340-5.
To determine the relation between right ventricular hypertrophy and right ventricular myocardial infarction in patients with chronic lung disease, the records of 28 patients with chronic lung disease, inferior myocardial infarction and significant coronary artery disease (group I) and 20 patients with right ventricular hypertrophy, chronic lung disease without inferior myocardial infarction or significant coronary artery disease (group II) were reviewed. Chronic lung disease was diagnosed by clinical criteria, chest radiographs and pulmonary function tests. All patients had postmortem examinations. Patients in group I were classified into two subgroups: group Ia (without right ventricular hypertrophy) and group Ib (with right ventricular hypertrophy). Right ventricular wall thickness was 3.3 mm +/- 0.5 in group Ia, 6.0 mm +/- 1.1 in group Ib and 8.8 mm +/- 2.4 in group II (group Ia versus Ib, p less than 0.001; group Ia versus II, p less than 0.001; group Ib versus II, p less than 0.001). Eleven patients (78.6%) in group Ib (chronic lung disease with both right ventricular hypertrophy and inferior myocardial infarction) had right ventricular myocardial infarction compared with only 3 patients (21.9%) in group Ia (chronic lung disease without right ventricular hypertrophy and with inferior myocardial infarction) (p less than 0.008). Isolated right ventricular myocardial infarction occurred in four patients (20%) in group II (chronic lung disease with right ventricular hypertrophy, but without evidence of infarction of the left ventricle or significant coronary artery disease). There was no significant difference in the extent of anatomic coronary disease in groups Ia and Ib.(ABSTRACT TRUNCATED AT 250 WORDS)
为了确定慢性肺病患者右心室肥厚与右心室心肌梗死之间的关系，回顾了28例患有慢性肺病、下壁心肌梗死和严重冠状动脉疾病的患者（第一组）以及20例患有右心室肥厚、无下壁心肌梗死或严重冠状动脉疾病的慢性肺病患者（第二组）的病历。慢性肺病通过临床标准、胸部X光片和肺功能测试进行诊断。所有患者均接受了尸检。第一组患者分为两个亚组：第一a组（无右心室肥厚）和第一b组（有右心室肥厚）。第一a组右心室壁厚度为3.3毫米±0.5，第一b组为6.0毫米±1.1，第二组为8.8毫米±2.4（第一a组与第一b组相比，p<0.001；第一a组与第二组相比，p<0.001；第一b组与第二组相比，p<0.001）。第一b组（患有右心室肥厚和下壁心肌梗死的慢性肺病）中有11例患者（78.6%）发生了右心室心肌梗死，而第一a组（无右心室肥厚但患有下壁心肌梗死的慢性肺病）中只有3例患者（21.9%）发生了右心室心肌梗死（p<0.008）。第二组（患有右心室肥厚但无左心室梗死或严重冠状动脉疾病证据的慢性肺病）中有4例患者（20%）发生了孤立性右心室心肌梗死。第一a组和第一b组在解剖学上的冠状动脉疾病程度无显著差异。（摘要截断于250字）
