Sena Israel Alexandre de Araújo, Silva Davi Neto de Araújo, Azevedo Marcela Letícia da Silva, da Silva Natália Teixeira, Longo João Paulo Figueiró, de Moraes Maiara, de Aquino Martins Ana Rafaela Luz
Dentistry Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasília, Brasília/DF, Brazil.
Photobiomodul Photomed Laser Surg. 2019 Nov;37(11):729-735. doi: 10.1089/photob.2019.4651. Epub 2019 Oct 7.
To evaluate the effects of antimicrobial photodynamic therapy (aPDT) with chloro-aluminum phthalocyanine (AlClFc) adjuvant to scaling and root planing (SRP) on periodontal clinical parameters of patients with chronic periodontitis. Fifty-four periodontal sites were randomly distributed into two groups: 27 in the test group (SRP+aPDT)-using a low-power laser application Photon Lase III (DMC Equipamentos Ltda, São Carlos, São Paulo, Brazil) with operational parameters of 660 nm and 100 mW for 15 sec, and 27 in the control group (SRP). SRP was performed in a single session and the periodontal clinical parameters such as visible plaque index, bleeding on probing (BOP), probing depth (PD), and clinical attachment level were assessed at the baseline (T) and 3 months after aPDT (T). Regarding BOP, a decrease in both treatment groups, the test group ( = 0.003) and control group ( = 0.001), was reported between T and T. A reduction in PD and clinical insertion gain for both treatment groups ( < 0.05) after 3 months of therapy was observed, although nonsignificant ( > 0.05) in intergroup comparison. aPDT with AlClFc adjuvant to SRP did not provide additional benefits in reducing PD and clinical insertion gain.
评估使用氯铝酞菁(AlClFc)辅助龈上洁治术和根面平整术(SRP)的抗菌光动力疗法(aPDT)对慢性牙周炎患者牙周临床参数的影响。54个牙周部位被随机分为两组:试验组(SRP + aPDT)27个部位,使用低功率激光设备Photon Lase III(DMC Equipamentos Ltda,巴西圣保罗州圣卡洛斯),操作参数为660nm和100mW,持续15秒;对照组(SRP)27个部位。SRP在单次治疗中进行,在基线期(T)和aPDT治疗后3个月(T)评估牙周临床参数,如可见菌斑指数、探诊出血(BOP)、探诊深度(PD)和临床附着水平。关于BOP,在T和T之间,试验组(P = 0.003)和对照组(P = 0.001)均有下降。治疗3个月后,两组的PD和临床附着水平均有所降低(P < 0.05),尽管组间比较无统计学意义(P > 0.05)。AlClFc辅助SRP的aPDT在降低PD和临床附着水平方面未提供额外益处。