Babaskin Dmitrii Vladimirovich, Litvinova Tatiana Mikhailovna, Babaskina Liudmila Ivanovna
Sechenov First Moscow State Medical University 8-2, Trubetskaya Street, Moscow, Russian Federation.
Open Access Maced J Med Sci. 2019 Jul 13;7(14):2236-2241. doi: 10.3889/oamjms.2019.603. eCollection 2019 Jul 30.
Improving the effectiveness of rehabilitation of patients with osteoarthritis necessitates the use of drug electrophoresis with sinusoidal modulated currents (SMC-electrophoresis) in conjunction with drug therapy. The phytocomplex is proposed for electrophoresis composed of the compared, alfalfa and hops dry extract, containing flavonoids, coumestans, polysaccharides, steroids, essential amino acids, vitamins, mineral components and causing its possible use in osteoarthritis.
The research aims to study the effect of the phytocomplex SMC-electrophoresis on the clinical symptoms and quality of life of patients with the knee joint osteoarthritis.
One hundred and eight patients were randomly distributed into 3 groups (n = 36). The phytocomplex SMC-electrophoresis was assigned to the first group, the amplipulse therapy (SMC) - to the second group, and the "basic" drug therapy - to the third group. The drug therapy of the patients of the third group was comparable with the drug treatment of those in the first two groups. The concentration of phytocomplex in the working solution was 10%. The electrotherapy was carried out in the aligned SMC mode in the first and fourth kind of works. Comparative indicators were as follows: WOMAC index, pain level on a visual analogue scale (VAS), Lequesne index, joint range of motion (JROM), articular and tendon indices, quality of life as per Health Assessment Questionnaire (HAQ).
The use of the phytocomplex SMC-electrophoresis had a more pronounced positive effect on pain, knee joint function and quality of life of the patients compared with the treatment with drugs alone or using amplitude therapy. This was especially pronounced immediately after the rehabilitation. The analgesic effect was consistently maintained in the patients of the first group for up to 6 - 12 months, the second group - up to 3 - 6 months in terms of the level of pain according to the WOMAC and Lequesne indices, VAS, articular and tendon indices. Stable results have been obtained for improving the functions of the knee joint for up to 6 - 12 months using the phytocomplex SMC-electrophoresis as per the WOMAC and Lequesne indices. In the treatment by the phytocomplex SMC-electrophoresis, no side effects were registered.
The obtained results give grounds for further research on the evaluation of the effectiveness of using the phytocomplex SMC-electrophoresis in microcirculatory disorders in the affected joint, for correcting connective tissue metabolism and electrolyte metabolism in the patients with the knee joint osteoarthritis.
提高骨关节炎患者的康复效果需要将正弦调制电流药物电泳（SMC 电泳）与药物治疗相结合。有人提出将一种植物复合物用于电泳，该复合物由紫花苜蓿和啤酒花干提取物组成，含有黄酮类化合物、香豆雌酚、多糖、类固醇、必需氨基酸、维生素、矿物质成分，使其有可能用于骨关节炎的治疗。
本研究旨在探讨植物复合物 SMC 电泳对膝关节骨关节炎患者临床症状和生活质量的影响。
108 例患者随机分为 3 组（n = 36）。第一组采用植物复合物 SMC 电泳，第二组采用音频脉冲疗法（SMC），第三组采用“基础”药物治疗。第三组患者的药物治疗与前两组相当。工作溶液中植物复合物的浓度为 10%。电疗法以对齐的 SMC 模式在第一类和第四类工作中进行。比较指标如下：WOMAC 指数、视觉模拟量表（VAS）疼痛水平、Lequesne 指数、关节活动范围（JROM）、关节和肌腱指数、根据健康评估问卷（HAQ）得出的生活质量。
与单纯药物治疗或音频脉冲疗法相比，使用植物复合物 SMC 电泳对患者的疼痛、膝关节功能和生活质量有更明显的积极影响。这在康复后立即尤为明显。根据 WOMAC 和 Lequesne 指数、VAS、关节和肌腱指数，第一组患者的镇痛效果持续维持长达 6 - 12 个月，第二组长达 3 - 6 个月。根据 WOMAC 和 Lequesne 指数，使用植物复合物 SMC 电泳改善膝关节功能长达 6 - 12 个月取得了稳定的结果。在植物复合物 SMC 电泳治疗中，未记录到副作用。
所得结果为进一步研究评估植物复合物 SMC 电泳在受影响关节微循环障碍中的有效性、纠正膝关节骨关节炎患者的结缔组织代谢和电解质代谢提供了依据。
