Technische Universität Dresden, Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Tatzberg 47/49, 01307 Dresden, Germany.
Centre for Neuroscience and Nanotechnology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Curr Biol. 2019 Oct 7;29(19):R930-R932. doi: 10.1016/j.cub.2019.08.013.
A new study reports an unexpected function of the nucleolus as a protein quality control compartment for misfolded and aggregation-prone proteins. These findings have important implications for protein misfolding diseases.
一项新的研究报告指出核仁作为一个蛋白质质量控制区的一个意想不到的功能，对于错误折叠和易于聚集的蛋白质。这些发现对蛋白质错误折叠疾病具有重要意义。
