沃莱塔苏多大学教学转诊医院成人艾滋病毒感染者贫血及其相关因素。
Anemia and its associated factors among adult people living with human immunodeficiency virus at Wolaita Sodo University teaching referral hospital.
机构信息
Wolaita Sodo University Teaching Referral Hospital, Wolaita Sodo, South Ethiopia.
School of Public Health, College of Medicine and Health Sciences, Wolaita Sodo University, Wolaita Sodo, South Ethiopia.
出版信息
PLoS One. 2019 Oct 9;14(10):e0221853. doi: 10.1371/journal.pone.0221853. eCollection 2019.
BACKGROUND
In Sub-Saharan Africa, both HIV/AIDS and anemia have considerable public health problems. Anemia has an adverse effect on treatment outcome and it decreases the quality of life among adult HIV patients. This study was aimed to assess the prevalence of anemia and its associated factors among adult HIV positive patients in Wolaita Sodo University Teaching Referral Hospital.
METHOD
Institution based cross-sectional study was conducted at Wolaita Sodo University Teaching Referral Hospital from 01 October to December 30, 2016. A randomly selected 411 adult people living with the human immunodeficiency virus were included in the study. A pre-tested questionnaire was used to collect data. Variables with P-value ≤0.25 in the bivariable logistic regression model were taken into multivariable logistic regression analysis along with 95% confidence interval and Odds Ratio was used to examine the association between anemia and independent variables. P-value ≤ 0.05 was taken as statistically significant.
RESULT
Prevalence of anemia in this study was 36.5% with 95% CI (32%-41%). Factors associated with anemia among adult people living with HIV/AIDS were individuals who lived with HIV ≥9years (AOR = 2.6, 95% CI:-1.03-6.59),years lived with HIV 5-8 years (AOR = 2.59, 95% CI:-1.02-6.57),CD4 count <200cells/ul (AOR = 4.2, 95%CI:-2.03-8.67), CD4 count200-350cells/ul(AOR = 1.82,95%CI:-1.01-3.26),infection with intestinal parasites (AOR = 2.04, 95% CI:-1.06-3.95), Participants with BMI <18.5kg/m2 (AOR = 2.96, 95%CI:-1.37-6.390),BMI 18.5-25kg/m2(AOR = 1.98, 95%CI:-1.11-3.56) and being HAART naïve (AOR = 2.23, 95% CI:- 1.16-4.28).
CONCLUSION
Prevalence of anemia among this study participant was high. This may affect the treatment outcome, increases morbidity and mortality of the participants. So periodic screening of anemia, a routine checkup of nutritional status, CD4 count and examination for intestinal parasite are essential.
背景
在撒哈拉以南非洲，艾滋病毒/艾滋病和贫血都存在相当大的公共卫生问题。贫血对治疗结果有不利影响，会降低成年艾滋病毒感染者的生活质量。本研究旨在评估沃莱塔索多大学教学转诊医院成年艾滋病毒阳性患者贫血的患病率及其相关因素。
方法
2016 年 10 月 1 日至 12 月 30 日，在沃莱塔索多大学教学转诊医院进行了一项基于机构的横断面研究。将 411 名随机选择的成年艾滋病毒感染者纳入研究。使用预先测试的问卷收集数据。在单变量逻辑回归模型中 P 值≤0.25 的变量，连同 95%置信区间和比值比一起纳入多变量逻辑回归分析，以检查贫血与独立变量之间的关系。P 值≤0.05 被认为具有统计学意义。
结果
本研究中贫血的患病率为 36.5%，95%CI（32%-41%）。与成人艾滋病毒感染者贫血相关的因素包括：艾滋病毒感染时间≥9 年（AOR=2.6，95%CI：-1.03-6.59）、艾滋病毒感染时间 5-8 年（AOR=2.59，95%CI：-1.02-6.57）、CD4 计数<200 个细胞/ul（AOR=4.2，95%CI：-2.03-8.67）、CD4 计数 200-350 个细胞/ul（AOR=1.82，95%CI：-1.01-3.26）、感染肠道寄生虫（AOR=2.04，95%CI：-1.06-3.95）、BMI<18.5kg/m2（AOR=2.96，95%CI：-1.37-6.39）、BMI 18.5-25kg/m2（AOR=1.98，95%CI：-1.11-3.56）和未接受抗逆转录病毒治疗（AOR=2.23，95%CI：-1.16-4.28）。
结论
本研究参与者贫血的患病率较高。这可能会影响治疗结果，增加参与者的发病率和死亡率。因此，定期筛查贫血、常规检查营养状况、CD4 计数和肠道寄生虫检查至关重要。
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