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单次大剂量维生素 D 可改善维生素 D 缺乏的年轻业余足球运动员的部分身体变量:一项随机对照试验。

A single mega dose of vitamin D improves selected physical variables in vitamin D-deficient young amateur soccer players: a randomized controlled trial.

机构信息

University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES11, Rabta Hospital, Laboratory of Biochemistry, 1007 Tunis, Tunisia.

National Center of Medicine and Sciences in Sports, Tunisian Research Laboratory "Sport Performance Optimization", 2010 Tunis, Tunisia.

出版信息

Appl Physiol Nutr Metab. 2020 May;45(5):478-485. doi: 10.1139/apnm-2019-0525. Epub 2019 Oct 9.

Abstract

This randomized controlled trial aimed to test whether vitamin D (VD) supplementation affects measures of physical performance in VD-deficient, mildly trained children. Thirty-six recreationally soccer player boys were randomly assigned to single dose (200 000 IU) of VD3 ( = 19) or placebo ( = 17). Plasma 25-hydroxyvitamin D (25-OHD) was assessed and measures of physical performance (i.e., vertical and standing broad jumps, triple hop, 10-m and 30-m sprints, shuttle run) were performed before and 12 weeks after the loading dose. Mixed ANCOVA models were performed and effect size was estimated by partial eta squared (η). Baseline 25-OHD and physical variables were equivalent in the 2 groups. Twelve weeks after VD loading, plasma 25-OHD increased and physical variables improved only in the VD group. There was a significant interaction effects for group by time for vertical jump ( = 14.9, = 0.001, η = 0.394), triple hop jump ( = 24.2, < 0.001, η = 0.513), 10-m ( = 4.46, = 0.046, η = 0.162) and 30-m ( = 6.56, = 0.017, η = 0.222) sprints, and shuttle run ( = 13.4, = 0.001, η = 0.369). In conclusion, a single bolus of VD3 resulted in significant improvements in jumping ability, agility, and running speed in mildly trained children that are deficient in VD. The findings suggest that correcting VD deficit might be beneficial for physical performance. A mega dose of VD3 improves jumping ability, agility, and running speed in VD-deficient, mildly trained children. Effect of VD on measures of physical performance is noticeable 3 months after the loading dose.

摘要

这项随机对照试验旨在测试维生素 D(VD)补充剂是否会影响 VD 缺乏、轻度训练的儿童的身体表现测量值。36 名业余足球运动员男孩被随机分配到单次剂量(200,000 IU)VD3(=19)或安慰剂(=17)。在负荷剂量前和 12 周后评估血浆 25-羟维生素 D(25-OHD),并进行身体表现测量(即垂直跳和站立跳远、三跳、10 米和 30 米冲刺、穿梭跑)。进行混合方差分析模型,并通过部分 eta 平方(η)估计效应大小。2 组的基线 25-OHD 和身体变量在统计学上是等效的。VD 负荷 12 周后,血浆 25-OHD 增加,仅在 VD 组中身体变量得到改善。组间存在显著的交互作用时间对于垂直跳跃(=14.9,=0.001,η=0.394)、三跳跳跃(=24.2,<0.001,η=0.513)、10 米(=4.46,=0.046,η=0.162)和 30 米(=6.56,=0.017,η=0.222)冲刺和穿梭跑(=13.4,=0.001,η=0.369)。总之,单次 VD3 剂量可显著改善 VD 缺乏、轻度训练的儿童的跳跃能力、敏捷性和跑步速度。研究结果表明,纠正 VD 缺乏可能对身体表现有益。大剂量 VD3 可改善 VD 缺乏、轻度训练儿童的跳跃能力、敏捷性和跑步速度。负荷剂量后 3 个月即可观察到 VD 对身体表现测量值的影响。

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