Calomeni Guilherme D, Ataíde Elaine B, Machado Ricardo R, Escanhoela Cecília A F, Costa Larissa B E, Boin Ilka F F
Rua Carlos Chagas, 420 (Setor de Transplante Hepático) - Cidade Universitária, Campinas 13083-878, SP, Brazil.
Int J Surg Case Rep. 2013;4(3):308-11. doi: 10.1016/j.ijscr.2013.01.002. Epub 2013 Jan 17.
Inflammatory pseudotumor (IPT) is a rare lesion consisted of inflammatory and myofibroblastic cells. These lesions may be found in different organs. There are less than 300 described cases.
Case 1. 64-year-old cirrhotic male with a palpable epigastric mass. CT showed a lesion in liver segments 2 and 3 and left hepatic artery aneurism. Percutaneous embolization and wide spectrum antibiotics were tried, however the lesion grew. Left lateral hepatectomy was performed, and HIPT diagnosed. The patient died due to multiple organ dysfunction. Case 2. 30-year-old male with abdominal pain and fever. CT showed a hepatic hilar lesion. Surgical resection was performed after an ineffectual antibiotic trial, and HIPT was confirmed. The patient is doing well. Case 3. 73-year-old female with abdominal pain and fever. CT showed a 7cm lesion in the left liver lobe. Unrewarding cancerous screening was performed, and unsuccessful antibiotic course was tried. Resection was performed, and HIPT diagnosed. The patient is doing well. Case 4. 50-year-old cirrhotic male with abdominal pain. CT showed a segment 6 lesion and portal vein thrombosis. Considering cancer as the first hypothesis and the MELD score of 9, segmentectomy was performed. HIPT was the final diagnosis. The patient died due to abdominal sepsis.
HIPT is a lesion with a vast list of differential diagnosis. Antibiotics are the first line of therapy, although surgery is often necessary. Overall prognosis is good, although comorbidities may worsen it.
HIPT is a rare and misleading entity.
炎性假瘤(IPT)是一种由炎症细胞和肌成纤维细胞组成的罕见病变。这些病变可出现在不同器官。目前报道的病例不足300例。
病例1。一名64岁的肝硬化男性,上腹部可触及肿块。CT显示肝段2和3有病变以及左肝动脉动脉瘤。尝试了经皮栓塞和广谱抗生素治疗,但病变仍在增大。实施了左肝外侧叶切除术,诊断为HIPT。患者因多器官功能障碍死亡。病例2。一名30岁男性,有腹痛和发热症状。CT显示肝门部有病变。抗生素治疗无效后进行了手术切除,确诊为HIPT。患者情况良好。病例3。一名73岁女性,有腹痛和发热症状。CT显示左肝叶有一个7cm的病变。进行了无果的癌症筛查,并尝试了无效的抗生素疗程。实施了切除术,诊断为HIPT。患者情况良好。病例4。一名50岁的肝硬化男性,有腹痛症状。CT显示肝段6有病变和门静脉血栓形成。最初考虑为癌症,MELD评分为9,实施了肝段切除术。最终诊断为HIPT。患者因腹部感染死亡。
HIPT是一种鉴别诊断繁多的病变。抗生素是一线治疗方法,不过手术往往也是必要的。总体预后良好,尽管合并症可能会使其恶化。
HIPT是一种罕见且易误诊的疾病。