Charles D A, Barber H O, Hope-Gill H F
J Otolaryngol. 1979 Aug;8(4):347-53.
Nineteen patients with unilateral Ménière's disease, 20 with psychogenic dizziness, and 20 with recurrent vestibulopathy (diagnostic criteria in text of paper) were found to have normal five hour glucose tolerance tests, serum thyroxine and effective thyroid indices, and serologic tests for syphilis. Hypothyroidism and hypoglycemia were absent in all groups. An unexplained finding of each diagnostic group was significant increase of fasting blood glucose and insulin levels, and elevated insulin:glucose ratios, compared to a control group. There appears to be no diagnostic indication for performing these chemical and serologic studies in patients with unilateral Ménière's disease, psychogenic vertigo, or recurrent vestibulopathy. Reasons are given to support the view that recurrent vestibulopathy may be a specific vestibular disturbance.
19例单侧梅尼埃病患者、20例精神性眩晕患者和20例复发性前庭病患者(诊断标准见论文正文)的5小时葡萄糖耐量试验、血清甲状腺素和有效甲状腺指数以及梅毒血清学检查均正常。所有组均未发现甲状腺功能减退和低血糖。与对照组相比,每个诊断组均有一个无法解释的发现,即空腹血糖和胰岛素水平显著升高,胰岛素与葡萄糖比值升高。对于单侧梅尼埃病、精神性眩晕或复发性前庭病患者,进行这些化学和血清学研究似乎没有诊断意义。文中给出了支持复发性前庭病可能是一种特定前庭障碍这一观点的理由。