用于耳鼻咽喉科临床应用的3D打印技术。
3D printing for clinical application in otorhinolaryngology.
作者信息
Zhong Nongping, Zhao Xia
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital, Fudan University, 12 Middle Wu Lu Mu Qi Road, Shanghai, 200040, China.
出版信息
Eur Arch Otorhinolaryngol. 2017 Dec;274(12):4079-4089. doi: 10.1007/s00405-017-4743-0. Epub 2017 Sep 19.
Three-dimensional (3D) printing is a promising technology that can use a patient's image data to create complex and personalized constructs precisely. It has made great progress over the past few decades and has been widely used in medicine including medical modeling, surgical planning, medical education and training, prosthesis and implants. Three-dimensional (3D) bioprinting is a powerful tool that has the potential to fabricate bioengineered constructs of the desired shape layer-by-layer using computer-aided deposition of living cells and biomaterials. Advances in 3D printed implants and future tissue-engineered constructs will bring great progress to the field of otolaryngology. By integrating 3D printing into tissue engineering and materials, it may be possible for otolaryngologists to implant 3D printed functional grafts into patients for reconstruction of a variety of tissue defects in the foreseeable future. In this review, we will introduce the current state of 3D printing technology and highlight the applications of 3D printed prosthesis and implants, 3D printing technology combined with tissue engineering and future directions of bioprinting in the field of otolaryngology.
三维(3D)打印是一项很有前景的技术,它可以利用患者的图像数据精确创建复杂的个性化结构。在过去几十年里它取得了巨大进展,并已广泛应用于医学领域,包括医学建模、手术规划、医学教育与培训、假体和植入物。三维(3D)生物打印是一种强大的工具,有潜力通过计算机辅助沉积活细胞和生物材料逐层制造出所需形状的生物工程结构。3D打印植入物和未来组织工程结构的进展将给耳鼻喉科领域带来巨大进步。通过将3D打印整合到组织工程和材料中,在可预见的未来,耳鼻喉科医生有可能将3D打印的功能性移植物植入患者体内,以重建各种组织缺损。在这篇综述中,我们将介绍3D打印技术的现状,并重点介绍3D打印假体和植入物的应用、3D打印技术与组织工程的结合以及生物打印在耳鼻喉科领域的未来发展方向。