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前庭植入物:真的有效吗?系统评价。

Vestibular implant: does it really work? A systematic review.

机构信息

Universidade de Brasília (UnB), Faculdade de Ciências de Saúde, Programa de Pós-Graduação em Ciências da Saúde, Brasília, DF, Brazil.

Universidade de Brasília (UnB), Programa de Ciências da Saúde, Brasília, DF, Brazil; Centro Universitário Planalto do Distrito Federal (UNIPLAN), Curso de Fonoaudiologia, Brasília, DF, Brazil; Faculdade de Ciências de Saúde ‒ Asa Norte, Brasília, DF, Brazil.

出版信息

Braz J Otorhinolaryngol. 2019 Nov-Dec;85(6):788-798. doi: 10.1016/j.bjorl.2019.07.011. Epub 2019 Sep 20.

Abstract

INTRODUCTION

People with vestibular loss present a deficit in the vestibular system, which is primarily responsible for promoting postural control, gaze stabilization, and spatial orientation while the head moves. There is no effective treatment for a bilateral loss of vestibular function. Recently, a vestibular implant was developed for people with bilateral loss of vestibular function to improve this function and, consequently, the quality of life of these patients.

OBJECTIVE

To identify in the scientific literature evidence that vestibular implants in people with vestibular deficit improves vestibular function.

METHODS

One hundred and forty six articles were found from five databases and 323 articles from the gray literature mentioning the relationship between vestibular implant and vestibular function in humans. The PICOS strategy (Population, Intervention, Comparison and Outcome) was used to define the eligibility criteria. The studies that met the inclusion criteria for this second step were included in a qualitative synthesis, and each type of study was analyzed according to the bias risk assessment of the Joanna Briggs Institute through the critical assessment checklist Joanna Briggs institute for quasi-experimental studies and the Joanna Briggs institute critical assessment checklist for case reports.

RESULTS

Of the 21 articles included in reading the full text, 10 studies were selected for the qualitative analysis in the present systematic review. All ten articles analyzed through the critical assessment checklist Joanna Briggs institute showed a low risk of bias. The total number of samples in the evaluated articles was 18 patients with vestibular implants.

CONCLUSIONS

Taken together, these findings support the feasibility of vestibular implant for restoration of the vestibulo-ocular reflex in a broad frequency range and illustrate new challenges for the development of this technology.

摘要

简介

患有前庭功能丧失的人会出现前庭系统缺陷,该系统主要负责在头部移动时促进姿势控制、凝视稳定和空间定位。目前,对于双侧前庭功能丧失,还没有有效的治疗方法。最近,一种前庭植入物被开发出来,用于治疗双侧前庭功能丧失的患者,以改善该功能,并最终提高这些患者的生活质量。

目的

在科学文献中确定前庭植入物是否可以改善患有前庭功能减退的人的前庭功能。

方法

从五个数据库中发现了 146 篇文章,从灰色文献中发现了 323 篇文章,这些文章都提到了人类前庭植入物与前庭功能之间的关系。采用 PICOS 策略(人群、干预、比较和结果)来定义纳入标准。符合纳入标准的研究纳入定性综合分析,并根据乔安娜·布里格斯研究所(Joanna Briggs Institute)的偏倚风险评估,对每种类型的研究进行分析,通过乔安娜·布里格斯研究所(Joanna Briggs Institute)的偏倚风险评估对准实验研究进行评估,以及乔安娜·布里格斯研究所(Joanna Briggs Institute)的偏倚风险评估对病例报告进行评估。

结果

在阅读全文的 21 篇文章中,有 10 篇被选中进行本系统评价的定性分析。通过乔安娜·布里格斯研究所(Joanna Briggs Institute)的偏倚风险评估对这 10 篇文章进行分析,结果均显示低偏倚风险。在评估的文章中,总样本数为 18 例接受前庭植入物治疗的患者。

结论

综上所述,这些研究结果支持前庭植入物在广泛的频率范围内恢复前庭眼反射的可行性,并为这项技术的发展提出了新的挑战。

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