Kerkhofs M, Hoffmann G, De Martelaere V, Linkowski P, Mendlewicz J
J Affect Disord. 1985 Jul;9(1):47-53. doi: 10.1016/0165-0327(85)90009-6.
Sleep polygraphic recordings were performed during 3 consecutive nights in a sample of 43 affectively ill inpatients. The patients were classified as major (n = 36) or minor depressive disorder (n = 7), according to the Research Diagnostic Criteria. Among the 36 patients with a major depressive disorder, 14 were in remission at the time of the sleep investigation. A two-way analysis of variance was performed to assess night and diagnostic effect on sleep variables. Shortening of REM latency was observed in depressed patients with major depressive disorder when compared to major depressive disorder patients in remission. Depressed patients with major depressive disorder also showed higher REM activity and REM density values than patients with minor depressive disorder. According to the linear discriminant analysis, sleep variables were able to correctly classify 68% of the patients.
对43名情感障碍住院患者进行了连续3晚的睡眠多导记录。根据研究诊断标准,患者被分为重度(n = 36)或轻度抑郁症(n = 7)。在36名重度抑郁症患者中,14名在睡眠调查时处于缓解期。进行了双向方差分析以评估夜间和诊断对睡眠变量的影响。与缓解期的重度抑郁症患者相比,重度抑郁症患者的快速眼动睡眠潜伏期缩短。重度抑郁症患者的快速眼动睡眠活动和快速眼动睡眠密度值也高于轻度抑郁症患者。根据线性判别分析,睡眠变量能够正确分类68%的患者。