Dahl R E, Puig-Antich J, Ryan N D, Nelson B, Dachille S, Cunningham S L, Trubnick L, Klepper T P
Department of Psychiatry, School of Medicine, University of Pittsburgh, PA.
J Affect Disord. 1990 May;19(1):63-75. doi: 10.1016/0165-0327(90)90010-6.
All night sleep EEG recordings were performed for three consecutive nights in 27 adolescents with a diagnosis of major depressive disorder (MDD) and 30 normal adolescent controls. Group comparisons between the entire MDD group and the normal controls revealed no significant diagnostic group differences for any of the major sleep variables. Analyses within subgroups of MDD adolescents, however, revealed heterogeneity of EEG sleep findings in association with suicidality and inpatient status. The findings of this study suggest that the discrepancies among the EEG sleep studies in adolescent MDD may be accounted for by the relative proportions of inpatients, suicidality, or bipolarity within the MDD sample being studied.
对27名被诊断为重度抑郁症（MDD）的青少年和30名正常青少年对照组进行了连续三晚的全夜睡眠脑电图记录。整个MDD组与正常对照组之间的组间比较显示，任何主要睡眠变量在诊断组之间均无显著差异。然而，对MDD青少年亚组的分析显示，脑电图睡眠结果与自杀倾向和住院状态相关存在异质性。本研究结果表明，青少年MDD脑电图睡眠研究之间的差异可能是由所研究的MDD样本中住院患者、自杀倾向或双相情感障碍的相对比例所致。
