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坚持地中海饮食与中年女性骨折风险:病例对照研究。

Adherence to the Mediterranean Diet and Bone Fracture Risk in Middle-Aged Women: A Case Control Study.

机构信息

Medicina Familiar i Comunitària (MFiC), Institut Català de la Salut, EAP Santa Clara, 17001 Girona, Spain.

DUI, Institut Català de la Salut, 17001 Girona, Spain.

出版信息

Nutrients. 2019 Oct 18;11(10):2508. doi: 10.3390/nu11102508.

DOI:10.3390/nu11102508
PMID:31635237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6835915/
Abstract

The prevention of bone mass loss and related complications associated with osteoporosis is a significant public health issue. The Mediterranean diet (MD) is favorably associated with bone health, a potentially modifiable risk factor. The objective of this research was to determine MD adherence in a sample of women with and without osteoporosis. In this observational case-control study of 139 women (64 women with and 75 without osteoporosis) conducted in a primary-care health center in Girona (Spain), MD adherence, lifestyle, physical exercise, tobacco and alcohol consumption, pathological antecedents, and FRAX index scores were analyzed. Logistic multilinear regression modeling to explore the relationship between the MD and bone fracture risk indicated that better MD adherence was associated with a lower bone risk fracture. Non-pharmacological preventive strategies to reduce bone fracture risk were also reviewed to explore the role of lifestyle and diet in bone mass maintenance and bone fracture prevention.

摘要

预防与骨质疏松症相关的骨量流失和相关并发症是一个重大的公共卫生问题。地中海饮食(Mediterranean diet,MD)与骨骼健康呈正相关,而骨骼健康是一个潜在可改变的危险因素。本研究旨在确定患有和不患有骨质疏松症的女性样本中的 MD 依从性。在西班牙赫罗纳的一个初级保健中心进行的这项观察性病例对照研究纳入了 139 名女性(64 名患有骨质疏松症,75 名没有),分析了 MD 依从性、生活方式、体育锻炼、吸烟和饮酒、既往病史以及 FRAX 指数评分。采用逻辑多元线性回归模型探索 MD 与骨折风险之间的关系表明,更好的 MD 依从性与较低的骨折风险相关。还回顾了非药物预防策略以降低骨折风险,以探讨生活方式和饮食在维持骨量和预防骨折方面的作用。

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