Han Shuying, Song Yilin, Kang An, Deng Haishan, Zhu Dong, Chi Yumei
College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Se Pu. 2019 Nov 8;37(11):1185-1192. doi: 10.3724/SP.J.1123.2019.04016.
A method was developed for the rapid determination of bisphenol A (BPA) and eight structural analogs in children's plastic water bottles by online enrichment coupled with high performance liquid chromatography-fluorescence detection (HPLC-FLD). The correlation coefficients of the nine bisphenols were greater than 0.998. The limits of detection (LOQs) ranged from 0.13 ng/L to 66.7 ng/L. The recoveries ranged from 90.7% to 112.4% (RSD<11.3%, =6). This method was applied to monitor nine bisphenols in children's water bottles. The results showed that except 4,4'-(9-fluoren-9-ylidene)bisphenol (BPFL), all the remaining eight bisphenols were detected in different water bottles. The amounts of bisphenols leached increased with the increase of soaking time, and decreased after washing several times at 100℃. The proposed strategy is rapid, sensitive, reliable and eco-friendly, and is suitable for the simultaneous analysis of new bisphenols in water samples.
建立了一种在线富集结合高效液相色谱-荧光检测（HPLC-FLD）快速测定儿童塑料水瓶中双酚A（BPA）及其8种结构类似物的方法。9种双酚的相关系数均大于0.998。检测限（LOQ）范围为0.13 ng/L至66.7 ng/L。回收率范围为90.7%至112.4%（RSD<11.3%，n = 6）。该方法应用于监测儿童水瓶中的9种双酚。结果表明，除4,4'-(9-芴亚基)双酚（BPFL）外，其余8种双酚均在不同水瓶中被检测到。双酚的溶出量随浸泡时间的增加而增加，在100℃下洗涤几次后减少。所提出的策略快速、灵敏、可靠且环保，适用于水样中新型双酚的同时分析。
