Bedin M, Fournier T, Mouhadjer N, Pointis G
INSERM U. 166, Groupe de Recherches sur l'Endocrinologie de la Reproduction, Paris, France.
J Steroid Biochem. 1988;30(1-6):439-41. doi: 10.1016/0022-4731(88)90138-0.
Steroid sulfatase (STS) activity was studied in Long-Evans rat testis. The affinity of the enzyme was shown to increase during postnatal development and to be always higher in purified Leydig cells than in seminiferous tubules. STS activity appeared to be higher in the seminiferous tubules at the earlier stages. In vivo injection of 100 IU hCG resulted in a decrease in the affinity and an increase in the activity of the enzyme expressed in Leydig cells with no such modification in seminiferous tubules. This suggests that STS could play a regulatory role in testosterone production by Leydig cells.
在Long-Evans大鼠睾丸中研究了类固醇硫酸酯酶（STS）活性。结果显示，该酶的亲和力在出生后发育过程中增加，并且在纯化的睾丸间质细胞中始终高于生精小管。在早期阶段，生精小管中的STS活性似乎更高。体内注射100 IU人绒毛膜促性腺激素（hCG）导致睾丸间质细胞中该酶的亲和力降低，活性增加，而生精小管中则无此变化。这表明STS可能在睾丸间质细胞产生睾酮的过程中发挥调节作用。
