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Clonality of CD4 Blood T Cells Predicts Longer Survival With CTLA4 or PD-1 Checkpoint Inhibition in Advanced Melanoma.
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CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
Clin Cancer Res. 2014 May 1;20(9):2424-32. doi: 10.1158/1078-0432.CCR-13-2648. Epub 2014 Feb 28.
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Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.
Cancer Immunol Res. 2018 Feb;6(2):139-150. doi: 10.1158/2326-6066.CIR-17-0134. Epub 2017 Nov 27.

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Biological and clinical significance of tumour-infiltrating lymphocytes in the era of immunotherapy: a multidimensional approach.
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Human TCR repertoire in cancer.
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Cancer immunotherapies: A hope for the uncurable?
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Development of a next-generation sequencing protocol for the canine T cell receptor beta chain repertoire.
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Neoadjuvant Therapy in Melanoma: Where Are We Now?
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Neoadjuvant immunotherapy of locoregionally advanced solid tumors.
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Heterogeneity and evolution of tumour immune microenvironment in metastatic gastroesophageal adenocarcinoma.
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Systemic treatments for metastatic cutaneous melanoma.
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.
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Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.
Cell. 2017 Nov 2;171(4):934-949.e16. doi: 10.1016/j.cell.2017.09.028. Epub 2017 Oct 12.
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Predicting response and toxicity to immune checkpoint inhibitors using routinely available blood and clinical markers.
Br J Cancer. 2017 Sep 26;117(7):913-920. doi: 10.1038/bjc.2017.274. Epub 2017 Aug 24.
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Dynamic Changes in PD-L1 Expression and Immune Infiltrates Early During Treatment Predict Response to PD-1 Blockade in Melanoma.
Clin Cancer Res. 2017 Sep 1;23(17):5024-5033. doi: 10.1158/1078-0432.CCR-16-0698. Epub 2017 May 16.
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Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire.
Cancer Res. 2017 Mar 15;77(6):1322-1330. doi: 10.1158/0008-5472.CAN-16-2324. Epub 2016 Dec 28.
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Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities.
Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11919-11924. doi: 10.1073/pnas.1611421113. Epub 2016 Oct 3.

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