Al-Khaldi Manal, Alsabbagh Manal
Registrar, Internal Medicine Department, King Hamad University Hospital, AL-Muharraq, Bahrain.
Registrar, Internal Medicine Department, Dermatology, King Hamad University Hospital, AL-Muharraq, Bahrain.
Case Rep Rheumatol. 2019 Sep 23;2019:7140534. doi: 10.1155/2019/7140534. eCollection 2019.
Isolated bilateral periorbital edema with negative serology is an extremely rare presentation of cutaneous lupus erythematosus that may lead to eyelid scarring, infection, or even corneal involvement. The treatment usually comprises a combination of hydroxychloroquine and a tapering dose of systemic steroids. Patients require long-term follow-up as they may develop systemic lupus erythematosus with positive serology later in life. We report a case of a 32-year-old female who presented with chronic bilateral periorbital edema, and the histopathology confirmed cutaneous lupus erythematosus.
血清学检查阴性的孤立性双侧眶周水肿是皮肤红斑狼疮极为罕见的表现，可能导致眼睑瘢痕、感染，甚至角膜受累。治疗通常包括羟氯喹和逐渐减量的全身性类固醇联合使用。患者需要长期随访，因为他们在晚年可能会出现血清学检查阳性的系统性红斑狼疮。我们报告一例32岁女性，她表现为慢性双侧眶周水肿，组织病理学证实为皮肤红斑狼疮。
