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实验约束的胰腺活检芯傅里叶变换红外成像高光谱数据集的无噪模拟。

Noise-free simulation of an FT-IR imaging hyperspectral dataset of pancreatic biopsy core bound by experiment.

机构信息

Institute of Nuclear Physics Polish Academy of Sciences, PL-31342, Krakow, Poland.

Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Mickiewicza 30, Krakow, Poland.

出版信息

Sci Data. 2019 Oct 29;6(1):239. doi: 10.1038/s41597-019-0260-x.

DOI:10.1038/s41597-019-0260-x
PMID:31664041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6820761/
Abstract

A noise-free hyperspectral FT-IR imaging dataset of a pancreatic tissue core was simulated based on experimental data that allows to test the performance of various data analysis and processing algorithms. A set of experimental noise levels was also added and used for denoising approaches comparison, which due to the noise-free reference signal enables to truly observe signal distortion caused by different approaches.

摘要

基于允许测试各种数据分析和处理算法性能的实验数据,模拟了无噪声高光谱傅里叶变换红外成像胰腺组织芯数据集。还添加了一组实验噪声水平,并用于去噪方法比较,由于无噪声参考信号,因此可以真正观察到不同方法引起的信号失真。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/1023c3a4092d/41597_2019_260_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/60787e040183/41597_2019_260_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/9b769b95cbfe/41597_2019_260_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/8b215e3b4629/41597_2019_260_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/bdc8a9cc7529/41597_2019_260_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/1023c3a4092d/41597_2019_260_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/60787e040183/41597_2019_260_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/9b769b95cbfe/41597_2019_260_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/8b215e3b4629/41597_2019_260_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/bdc8a9cc7529/41597_2019_260_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/6820761/1023c3a4092d/41597_2019_260_Fig5_HTML.jpg

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本文引用的文献

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Sci Rep. 2018 Sep 25;8(1):14351. doi: 10.1038/s41598-018-32713-7.
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Infrared Spectroscopic Imaging Advances as an Analytical Technology for Biomedical Sciences.红外光谱成像作为生物医学科学的一种分析技术取得进展。
Anal Chem. 2018 Feb 6;90(3):1444-1463. doi: 10.1021/acs.analchem.7b05330.
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SIproc: an open-source biomedical data processing platform for large hyperspectral images.
SIproc:一个用于大型高光谱图像的开源生物医学数据处理平台。
Analyst. 2017 Apr 10;142(8):1350-1357. doi: 10.1039/c6an02082h.
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High-resolution FTIR imaging of colon tissues for elucidation of individual cellular and histopathological features.用于阐明个体细胞和组织病理学特征的结肠组织高分辨率傅里叶变换红外成像
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High definition infrared spectroscopic imaging for lymph node histopathology.用于淋巴结组织病理学的高分辨率红外光谱成像
PLoS One. 2015 Jun 3;10(6):e0127238. doi: 10.1371/journal.pone.0127238. eCollection 2015.
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Quantification of plaque area and characterization of plaque biochemical composition with atherosclerosis progression in ApoE/LDLR(-/-) mice by FT-IR imaging.应用 FT-IR 成像技术定量分析载脂蛋白 E/LDLR(-/-) 小鼠动脉粥样硬化进展过程中的斑块面积和斑块生化成分特征。
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Analyst. 2012 Jan 21;137(2):322-32. doi: 10.1039/c1an15821j. Epub 2011 Nov 24.
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Application of FT-Raman spectroscopy for in situ detection of microorganisms on the surface of textiles.傅里叶变换拉曼光谱在纺织品表面微生物原位检测中的应用。
J Environ Monit. 2011 Nov;13(11):2983-7. doi: 10.1039/c1em10698h. Epub 2011 Sep 29.
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Resonant Mie scattering in infrared spectroscopy of biological materials--understanding the 'dispersion artefact'.生物材料红外光谱中的共振米氏散射——理解“色散伪像”。
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