Al Rstum Zain, Tanaka Akiko, Eisenberg Steven B, Estrera Anthony L
Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.
Ann Cardiothorac Surg. 2019 Sep;8(5):524-530. doi: 10.21037/acs.2019.07.08.
Acute type A aortic intramural hematomas (IMHs) are often included under the spectrum of acute aortic syndromes. The classical definition is the presence of hematoma in the media without identifiable intimal tear. Dissection occurring within two weeks of presentation is defined as acute. Acute type A IMH remains a subject of debate, especially regarding its definition and management. The classical theory of pathogenesis of IMHs is ruptured vasa vasorum in the aortic media. However, the majority of IMHs are now detected with an intimal defect using high-resolution computed tomography and intravascular ultrasound, which implies that IMHs may be a subset of aortic dissections (ADs), with very limited flow in the false lumen. Much controversy remains regarding IMH differences in presentation, diagnosis, and risk for progression. Geographic location and ethnicity, especially Asian . Western, possibly affect the natural history and outcomes of acute type A IMH. In this review, we describe the pathophysiology and management strategies for acute type A IMHs.
急性A型主动脉壁内血肿(IMH)常被纳入急性主动脉综合征范畴。经典定义为中膜存在血肿且无明确内膜撕裂。发病两周内发生的夹层被定义为急性。急性A型IMH仍是一个有争议的话题,尤其是在其定义和治疗方面。IMH的经典发病机制理论是主动脉中膜滋养血管破裂。然而,现在大多数IMH通过高分辨率计算机断层扫描和血管内超声检测到存在内膜缺损,这意味着IMH可能是主动脉夹层(AD)的一个子集,假腔内血流非常有限。关于IMH在表现、诊断和进展风险方面的差异仍存在很多争议。地理位置和种族,尤其是亚洲人与西方人,可能会影响急性A型IMH的自然病程和预后。在本综述中,我们描述了急性A型IMH的病理生理学和治疗策略。