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四肢骨骼转移瘤的管理原则

Principles of Management of Extremity Skeletal Metastasis.

作者信息

Gupta Srinath, Gulia Ashish, Kurisunkal Vineet, Parikh Mishil, Gupta Sanjay

机构信息

Department of Bone and Soft Tissue, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Department of Orthopaedics, DY Patil School of Medicine, Navi Mumbai, Maharashtra, India.

出版信息

Indian J Palliat Care. 2019 Oct-Dec;25(4):580-586. doi: 10.4103/IJPC.IJPC_90_19.

DOI:10.4103/IJPC.IJPC_90_19
PMID:31673216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6812423/
Abstract

Understanding the epidemiology of extremity skeletal metastasis and the factors deciding the treatment decision-making are essential in developing a diagnostic and treatment strategy. This leads to optimum care and reduces disease-related burden. With the evolution of medical, radiation therapy, and surgical methods, cancer care has improved the quality of life for patients with improved survival and functional status in patients with skeletal metastasis. Based on the currently available literature, we have described a step-wise evaluation and management strategy of metastatic extremity bone disease. The present review article addresses various aspects and related controversies related to evaluation, staging, and treatment options in the management of extremity bone metastasis. This article also highlights the role of multidisciplinary involvement in management of extremity skeletal metastasis.

摘要

了解四肢骨骼转移瘤的流行病学以及决定治疗决策的因素对于制定诊断和治疗策略至关重要。这有助于实现最佳治疗并减轻疾病相关负担。随着医学、放射治疗和手术方法的发展,癌症治疗提高了骨骼转移瘤患者的生活质量,改善了患者的生存和功能状态。基于现有文献,我们描述了转移性四肢骨病的逐步评估和管理策略。本综述文章探讨了四肢骨转移瘤管理中评估、分期和治疗选择的各个方面及相关争议。本文还强调了多学科参与在四肢骨骼转移瘤管理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/731f181885f3/IJPC-25-580-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/d0b0d2d19015/IJPC-25-580-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/953df639ef12/IJPC-25-580-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/418040a11544/IJPC-25-580-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/f18336854245/IJPC-25-580-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/ea31ebe323d5/IJPC-25-580-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/731f181885f3/IJPC-25-580-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/d0b0d2d19015/IJPC-25-580-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/953df639ef12/IJPC-25-580-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/418040a11544/IJPC-25-580-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/f18336854245/IJPC-25-580-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/ea31ebe323d5/IJPC-25-580-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a8d/6812423/731f181885f3/IJPC-25-580-g006.jpg

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本文引用的文献

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Cementoplasty of pelvic bone metastases: systematic assessment of lesion filling and other factors that could affect the clinical outcomes.骨盆骨转移瘤的骨水泥成形术:对病变填充及其他可能影响临床结果的因素的系统评估。
Skeletal Radiol. 2019 Sep;48(9):1345-1355. doi: 10.1007/s00256-019-3156-0. Epub 2019 Feb 2.
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Bone Metastases: An Overview.骨转移:概述
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CT-based Structural Rigidity Analysis Is More Accurate Than Mirels Scoring for Fracture Prediction in Metastatic Femoral Lesions.基于CT的结构刚度分析在预测股骨转移瘤骨折方面比米雷尔评分更准确。
Clin Orthop Relat Res. 2016 Mar;474(3):643-51. doi: 10.1007/s11999-015-4453-0.
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The surgical treatment of pelvic bone metastases.骨盆骨转移瘤的外科治疗
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Management of skeletal metastases: An orthopaedic surgeon's guide.骨转移瘤的管理:骨科医生指南
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[The treatment for cancer with bone metastases -whether to use zoledoronate or denosumab for bone metastases-].[癌症骨转移的治疗——骨转移是使用唑来膦酸盐还是地诺单抗治疗——]
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Insight opinion to surgically treated metastatic bone disease: Scandinavian Sarcoma Group Skeletal Metastasis Registry report of 1195 operated skeletal metastasis.手术治疗转移性骨病的观点:斯堪的纳维亚肉瘤组骨骼转移登记处报告 1195 例手术治疗骨骼转移。
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Treating metastatic disease: Which survival model is best suited for the clinic?治疗转移性疾病:哪种生存模型最适合临床?
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