Department of Psychiatry, University of Cambridge, UK; Cambridge and Peterborough NHS Foundation Trust, UK.
Department of Psychiatry, University of Cambridge, UK; Department of Kinanthropology, Charles University in Prague, Czechia; Cambridge and Peterborough NHS Foundation Trust, UK.
Prog Neuropsychopharmacol Biol Psychiatry. 2020 Mar 8;97:109799. doi: 10.1016/j.pnpbp.2019.109799. Epub 2019 Oct 30.
While many individuals gamble responsibly, some develop maladaptive symptoms of a gambling disorder. Gambling problems often first occur in young people, yet little is known about the longitudinal course of such symptoms and whether this course can be predicted. The aim of this study was to identify latent subtypes of disordered gambling based on symptom presentation and identify predictors of persisting gambling symptoms over time.
575 non-treatment seeking young adults (mean age [SD] = 22.3 [3.6] years; 376 (65.4%) male) were assessed at baseline and annually, over three years, using measures of gambling severity. Latent subtypes of gambling symptoms were identified using latent mixture modeling. Baseline differences were characterized using analysis of variance and binary logistic regression respectively.
Three longitudinal phenotypes of disordered gambling were identified: high harm group (N = 5.6%) who had moderate-severe gambling disorder at baseline and remained symptomatic at follow-up; intermediate harm group (19.5%) who had problem gambling reducing over time; and low harm group (75.0%) who were essentially asymptomatic. Compared to the low harm group, the other two groups had worse baseline quality of life, elevated occurrence of other mental disorders and substance use, higher body mass indices, and higher impulsivity, compulsivity, and cognitive deficits. Approximately 5% of the total sample showed worsening of gambling symptoms over time, and this rate did not differ significantly between the groups.
Three subtypes of disordered gambling were found, based on longitudinal symptom data. Even the intermediate gambling group had a profundity of psychopathological and untoward physical health associations. Our data indicate the need for large-scale international collaborations to identify predictors of clinical worsening in people who gamble, across the full range of baseline symptom severity from minimal to full endorsement of current diagnostic criteria for gambling disorder.
虽然许多人负责任地赌博,但有些人会出现赌博障碍的不良症状。赌博问题通常首先出现在年轻人身上,但人们对这些症状的纵向发展过程知之甚少,也不知道是否可以预测这种过程。本研究的目的是根据症状表现确定赌博障碍的潜在亚类型,并确定随时间推移持续存在赌博症状的预测因素。
575 名非治疗寻求的年轻成年人(平均年龄[标准差]为 22.3[3.6]岁;376 名[65.4%]为男性)在基线和 3 年内每年接受一次评估,使用赌博严重程度测量。使用潜在混合模型确定赌博症状的潜在亚类型。使用方差分析和二项逻辑回归分别描述基线差异。
确定了三种赌博障碍的纵向表型:高伤害组(N=5.6%)在基线时患有中度严重的赌博障碍,并在随访时仍有症状;中间伤害组(19.5%)的问题赌博随时间减少;低伤害组(75.0%)基本无症状。与低伤害组相比,其他两组的基线生活质量更差,其他精神障碍和物质使用的发生率更高,体重指数更高,冲动性、强迫性和认知缺陷更高。大约 5%的总样本在随时间推移时出现赌博症状恶化,而且各组之间的恶化率没有显著差异。
根据纵向症状数据,发现了三种赌博障碍亚类型。即使是中间赌博组也存在深刻的心理病理学和不良的身体健康关联。我们的数据表明,需要进行大规模的国际合作,以确定从轻度到完全符合当前赌博障碍诊断标准的基线症状严重程度范围内的所有人群中,哪些人存在赌博恶化的预测因素。