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基于蒙特卡罗模拟的伊朗饮茶氟暴露非致癌健康风险评估

Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation.

机构信息

Department of Environmental Health Engineering, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.

Department of Environmental Health Engineering, Student Research Committee, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Int J Environ Res Public Health. 2019 Nov 2;16(21):4261. doi: 10.3390/ijerph16214261.

Abstract

Excessive intake of fluoride can cause adverse health effects. Consumption of tea as a popular drink could be a potential source of fluoride exposure to humans. This research aimed to evaluate the fluoride concentration in tea among the Iranian people using the available data in the literature and to assess the health risk related to the consumption of tea in men, women, and children. The health risk assessment was conducted using the chronic daily intake and hazard quotient according to the approach suggested by the Environmental Protection Agency. The fluoride content in published studies varied noticeably, ranging from 0.13 to 3.27 mg/L. The results revealed that the hazard quotient (HQ) in age groups of women (21-72 years) and children (0-11 years) was within the safe zone (HQ < 1) which showed that there was no potential of non-carcinogenic risk associated with drinking tea in these groups. However, in one case of the men (21-72 years), the HQ > 1 which shows a probable risk of fluorosis. The order of non-carcinogenic health risks in the studied groups was in the order of men > women > children. The results of this can be useful for organizations with the responsibility of human health promotion.

摘要

过量摄入氟化物可能会对健康造成不良影响。茶作为一种受欢迎的饮品,可能是人类接触氟化物的潜在来源。本研究旨在利用文献中可用的数据评估伊朗人饮用茶中的氟化物浓度,并评估男性、女性和儿童饮茶相关的健康风险。健康风险评估采用了慢性日摄入量和危害系数的方法,该方法是根据环境保护署提出的方法得出的。已发表研究中的氟化物含量差异明显,范围为 0.13 至 3.27 毫克/升。结果表明,妇女(21-72 岁)和儿童(0-11 岁)年龄组的危害系数(HQ)处于安全区(HQ<1),这表明在这些组中,饮用茶没有与非致癌风险相关的潜在风险。然而,在一名 21-72 岁的男性中,HQ>1,这表明可能存在氟斑牙风险。在所研究的组中,非致癌健康风险的顺序为男性>女性>儿童。这些结果对于负责促进人类健康的组织可能是有用的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b93c/6862652/e7afde21e4de/ijerph-16-04261-g001.jpg

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