From the School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan (C-DL, J-YT); Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan (C-DL, S-WH, T-HL); Department of Orthopedics, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan (Y-SC); Department of Radiology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan (J-WK); Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan, Taiwan (S-WH); and Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (S-WH, T-HL).
Am J Phys Med Rehabil. 2020 May;99(5):381-389. doi: 10.1097/PHM.0000000000001344.
Knee osteoarthritis and age are associated with high sarcopenia risk, especially in patients who have received total knee replacement. The aim of this study was to identify the effects of elastic resistance exercise training after total knee replacement on muscle mass and physical outcomes in older women with knee osteoarthritis.
Sixty older women who received unilateral primary total knee replacement surgery were randomized to an experimental group, which received 12 wks of postoperative elastic resistance exercise training, or a control group, which received standard care. The outcome measures included physical function performance (ie, Timed Up & Go, gait speed, forward reach, single-leg stance, timed chair rise), appendicular lean mass, and the Western Ontario and McMaster Universities Osteoarthritis Index. The assessment time points were 2 wks before surgery (T0), 1 mo after surgery (T1, before resistance exercise training), and 4 mos after surgery (T2, upon completion of resistance exercise training).
After 12 wks of postoperative elastic resistance exercise training, the experimental group exhibited a significantly greater change in appendicular lean mass (mean difference = 0.81 kg, P = 0.004) than the control group. Elastic resistance exercise training also exerted significant effects on Timed Up & Go and gait speed with mean differences of 0.28 m/sec (P < 0.001) and -2.66 secs (P < 0.001), respectively.
A 12-wk elastic resistance exercise training program after total knee replacement exerted benefits on muscle mass, mobility, and Western Ontario and McMaster Universities Osteoarthritis Index functional outcomes in older women with knee osteoarthritis.
膝关节骨关节炎和年龄与高肌肉减少症风险相关，尤其是在接受全膝关节置换的患者中。本研究旨在确定全膝关节置换术后弹性抗阻训练对老年膝关节骨关节炎女性的肌肉质量和身体结果的影响。
60 名接受单侧初次全膝关节置换手术的老年女性被随机分为实验组，接受 12 周术后弹性抗阻训练；对照组接受标准护理。主要结局指标包括身体功能表现（即计时起立行走测试、步态速度、前伸距离、单腿站立、计时坐起）、四肢瘦体重和西安大略和麦克马斯特大学骨关节炎指数。评估时间点为术前 2 周（T0）、术后 1 个月（T1，在抗阻训练之前）和术后 4 个月（T2，在抗阻训练完成后）。
在术后 12 周弹性抗阻训练后，实验组的四肢瘦体重变化明显大于对照组（平均差异=0.81 公斤，P=0.004）。弹性抗阻训练还对计时起立行走测试和步态速度产生显著影响，平均差异分别为 0.28 米/秒（P<0.001）和-2.66 秒（P<0.001）。
全膝关节置换术后 12 周的弹性抗阻训练方案对老年膝关节骨关节炎女性的肌肉质量、活动能力和西安大略和麦克马斯特大学骨关节炎指数功能结局有获益。
