Wolfson A D, Orlovsky A F, Gladilin K L
A.N. Bakh Institute of Biochemistry, Academy of Sciences of the USSR, Moscow.
FEBS Lett. 1988 Oct 10;238(2):262-4. doi: 10.1016/0014-5793(88)80492-7.
The high-molecular-mass form of valyl-tRNA synthetase is associated with the first elongation factor activity. It includes two polypeptides of about 50 kDa and two others of 40 and 30 kDa, identified as alpha, beta, gamma and delta subunits of eEF-1H. The complex of valyl-tRNA synthetase with eEF-1H is suggested to be a novel form of the first elongation factor.
缬氨酰 - tRNA合成酶的高分子量形式与首个延伸因子活性相关。它包括两条约50 kDa的多肽以及另外两条40 kDa和30 kDa的多肽,分别被鉴定为eEF - 1H的α、β、γ和δ亚基。缬氨酰 - tRNA合成酶与eEF - 1H的复合物被认为是首个延伸因子的一种新形式。