Jonas J B, Gusek G C, Guggenmoos-Holzmann I, Naumann G O
Institut für Augenheilkunde und Augenklinik, Universität Erlangen-Nürnberg, Federal Republic of Germany.
Graefes Arch Clin Exp Ophthalmol. 1988;226(4):332-6. doi: 10.1007/BF02172962.
Using Littmann's method for correcting the magnification of central fundus photographs, we evaluated planimetrically the color slides of 88 unselected optic discs without evidence of any optic nerve disease. High myopes (less than -8.00 diopters) had been excluded. Mean optic disc area measured 2.89 +/- 0.76 mm2 (minimum 0.86 mm2, maximum 5.39 mm2), mean cup area 0.63 +/- 0.64 mm2 (minimum 0.00 mm2, maximum 3.10 mm2) and mean neuroretinal rim area 2.26 +/- 0.58 mm2 (minimum 0.86 mm2, maximum 3.84 mm2). Horizontal disc diameter ranged from 0.91 mm to 2.42 mm (mean 1.79 +/- 0.27 mm) and vertical diameter from 1.08 mm to 2.76 mm (mean 1.97 +/- 0.29 mm). Coefficients of variation of the method's reproducibility were 0.03 for intraobserver and 0.03 for interobserver determination. Regarding the Gaussian distribution curve based on these preliminary data, microdiscs can be defined as being smaller than 1.4 mm2 (mean minus two standard deviations) and macrodiscs as being larger than 4.4 mm2 (mean plus two standard deviations).
我们使用利特曼法校正中央眼底照片的放大倍数,通过平面测量法评估了88张未筛选的视盘彩色幻灯片,这些视盘均无任何视神经疾病的迹象。高度近视者(低于-8.00屈光度)已被排除。测得的平均视盘面积为2.89±0.76平方毫米(最小值0.86平方毫米,最大值5.39平方毫米),平均杯盘面积为0.63±0.64平方毫米(最小值0.00平方毫米,最大值3.10平方毫米),平均神经视网膜边缘面积为2.26±0.58平方毫米(最小值0.86平方毫米,最大值3.84平方毫米)。视盘水平直径范围为0.91毫米至2.42毫米(平均1.79±0.27毫米),垂直直径范围为1.08毫米至2.76毫米(平均1.97±0.29毫米)。该方法重复性的观察者内变异系数为0.03,观察者间变异系数为0.03。根据这些初步数据的高斯分布曲线,微小视盘可定义为小于1.4平方毫米(平均值减去两个标准差),而大视盘可定义为大于4.4平方毫米(平均值加上两个标准差)。