Delori F C, Fitch K A, Feke G T, Deupree D M, Weiter J J
Eye Research Institute of Retina Foundation, Boston, MA 02114.
Graefes Arch Clin Exp Ophthalmol. 1988;226(4):393-9. doi: 10.1007/BF02172974.
The width of retinal vessel images on fundus photographs was determined by projection micrometry and microdensitometry. These methods were evaluated on 12 retinal vessels using the negatives of 570-nm monochromatic fundus photographs. For projection micrometry, the intraobserver reproducibility of vessel width measurements was 1.6%-2.9%, depending upon the experience of the observer. Significant interobserver differences in the measured widths were demonstrated. For microdensitometry, three distinct measurement criteria were used. Significant differences in width as measured by the three criteria were found, but there were no interoperator differences for each criterion. The intraoperator reproducibility of vessel width measurements by microdensitometry was 2.1%-2.5%. Significant differences were found in the vessel widths determined by the micrometry and densitometry methods, and results obtained by micrometry are discussed in terms of edge-detection phenomena.
通过投影测微法和显微密度测定法确定眼底照片上视网膜血管图像的宽度。使用570纳米单色眼底照片的底片，对12条视网膜血管进行了这些方法的评估。对于投影测微法，血管宽度测量的观察者内再现性为1.6%-2.9%，这取决于观察者的经验。测量宽度显示出观察者间存在显著差异。对于显微密度测定法，使用了三种不同的测量标准。发现三种标准测量的宽度存在显著差异，但每种标准的操作员间没有差异。显微密度测定法测量血管宽度的操作员内再现性为2.1%-2.5%。发现通过测微法和密度测定法确定的血管宽度存在显著差异，并根据边缘检测现象讨论了测微法获得的结果。
