Ophthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.
Department of Surgical and Biomedical Sciences, Section of Ophthalmology, University of Perugia, S. Maria della Misericordia Hospital, Perugia, Italy.
Ocul Immunol Inflamm. 2021 Feb 17;29(2):340-345. doi: 10.1080/09273948.2019.1678650. Epub 2019 Nov 7.
: To evaluate choroidal structural changes in patients with multiple evanescent white dot syndrome (MEWDS) during the acute and recovery stages.: Enhanced-depth imaging optical coherence tomography (EDI-OCT) scans of 16 patients with unilateral MEWDS were acquired during the acute and recovery stages in both eyes. Images were binarized with the ImageJ software to measure subfoveal choroidal thickness (CT), total choroid area, luminal area and choroidal vascularity index (CVI).: In the acute stage, subfoveal CT, total choroidal area and CVI were significantly higher in eyes with MEWDS compared to fellow eyes (371.2 ± 101.8 vs 317.1 ± 90.3 µm, = .001; 2.826 ± 0.686 vs 2.524 ± 0.674 mm, = .014; 69.49 ± 3.51 vs 68.27 ± 3.41%, = .044, respectively). In the recovery stage, subfoveal CT, total choroidal area and CVI in eyes with MEWDS significantly decreased to respectively 333.4 ± 90.5 µm, = .007, 2.592 ± 0.570 = .002, and 67.31 ± 2.74%, = .014.: Choroidal thickness and vascularity are significantly increased during the acute stage of MEWDS.
评估多发性一过性白点综合征（MEWDS）患者在急性期和恢复期的脉络膜结构变化。
对 16 例单侧 MEWDS 患者的双眼在急性期和恢复期进行增强深度成像光学相干断层扫描（EDI-OCT）扫描。使用 ImageJ 软件对图像进行二值化处理，以测量中心凹下脉络膜厚度（CT）、总脉络膜面积、管腔面积和脉络膜血管指数（CVI）。
在急性期，MEWDS 眼的中心凹下 CT、总脉络膜面积和 CVI 均显著高于对侧眼（371.2±101.8 与 317.1±90.3μm， =0.001；2.826±0.686 与 2.524±0.674mm， =0.014；69.49±3.51 与 68.27±3.41%， =0.044）。在恢复期，MEWDS 眼的中心凹下 CT、总脉络膜面积和 CVI 分别显著下降至 333.4±90.5μm， =0.007，2.592±0.570 =0.002，67.31±2.74%， =0.014。
MEWDS 急性期脉络膜厚度和血管密度显著增加。
