a Department of Biomedical and Surgical Sciences, Section of Ophthalmology , University of Perugia, S. Maria della Misericordia Hospital , Perugia , Italy.
b Department of Internal Medicine , University of Perugia, S. Maria della Misericordia Hospital , Perugia , Italy.
Ocul Immunol Inflamm. 2018;26(3):428-434. doi: 10.1080/09273948.2016.1231329. Epub 2016 Oct 11.
To perform an analysis of optical coherence tomography (OCT) abnormalities in patients with MEWDS, during the acute and recovery stages, using enhanced depth imaging-OCT (EDI-OCT).
A retrospective case series of five patients with MEWDS was included. EDI-OCT imaging was evaluated to detect retinal and choroidal features.
In the acute phase, focal impairment of the ellipsoid zone and external limiting membrane, hyperreflective dots in the inner choroid, and full-thickness increase of the choroidal profile were observed in the affected eye; disappearance of these findings and restoration of the choroidal thickness (p = 0.046) was appreciated in the recovery phase. No OCT abnormalities were assessed in the unaffected eye.
EDI-OCT revealed transient outer retinal layer changes and inner choroidal hyperreflective dots. A transient increased thickness of the whole choroid was also identified. This might confirm a short-lasting inflammatory involvement of the whole choroidal tissue in the active phase of MEWDS.
使用增强深度成像光学相干断层扫描（EDI-OCT）分析急性和恢复期 MEWDS 患者的光学相干断层扫描（OCT）异常。
本研究纳入了 5 例 MEWDS 患者的回顾性病例系列。对 EDI-OCT 成像进行评估，以检测视网膜和脉络膜特征。
在急性期，受影响眼观察到椭圆体带和外界膜的局灶性损伤、脉络膜内层的高反射点以及脉络膜全层厚度增加；在恢复期，这些发现消失，脉络膜厚度恢复（p=0.046）。未受影响的眼未评估到 OCT 异常。
EDI-OCT 显示了短暂的外视网膜层变化和脉络膜内层高反射点。还发现整个脉络膜的厚度短暂增加。这可能证实了 MEWDS 活动期整个脉络膜组织的短暂炎症受累。
