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与冠状病毒感染相关的多发性一过性白点综合征:一例报告。

Multiple Evanescent White Dot Syndrome Associated with Coronavirus Infection: A Case Report.

机构信息

Eye Clinic, Clinical Center of Montenegro and Medical Faculty, University of Montenegro, Podgorica, Montenegro.

Eye Clinic, Clinical Center of Serbia, Belgrade, Serbia.

出版信息

Iran J Med Sci. 2023 Jan;48(1):98-101. doi: 10.30476/IJMS.2022.95007.2632.

Abstract

Coronavirus disease 2019 (COVID-19) causes ocular manifestations in approximately 11% of patients. Most patients typically develop ocular symptoms within 30 days of the onset of the first COVID-19 symptoms. The most common ocular manifestation is conjunctivitis, which affects nearly 89% of patients with eye problems. Other much less common anterior segment abnormalities caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are scleritis, episcleritis, and acute anterior uveitis. Posterior segment abnormalities caused by SARS-CoV-2 are mainly vascular, such as hemorrhages, cotton wool spots, dilated veins, and vasculitis. Herein, we report a rare manifestation of COVID-19 and multiple evanescent white dot syndrome (MEWDS) of the retina. In April 2021, a 40-year-old female patient was admitted to the Eye Clinic of Clinical Center of Montenegro (Podgorica, Montenegro). The patient's main complaint was sudden vision impairment, which occurred 14 days after a positive polymerase chain reaction (PCR) test result for SARS-CoV-2 infection. A complete eye examination was performed, followed by fundoscopy, optical coherence tomography (OCT), and fluorescein angiography (FA) tests. The results showed retinal changes associated with MEWDS. The patient underwent additional examinations to rule out common causes of multifocal retinitis, all of which were unremarkable. Therefore, it was concluded that retinitis was a complication of COVID-19. Given its non-invasive nature, fundus examination should be used as a standard screening method for retinal changes in patients with COVID-19.

摘要

2019 年冠状病毒病(COVID-19)在大约 11%的患者中引起眼部表现。大多数患者通常在 COVID-19 症状出现后的 30 天内出现眼部症状。最常见的眼部表现是结膜炎,影响近 89%的有眼部问题的患者。由严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的其他不太常见的前段异常包括巩膜炎、表层巩膜炎和急性前葡萄膜炎。由 SARS-CoV-2 引起的后段异常主要是血管性的,如出血、棉絮斑、扩张的静脉和血管炎。在此,我们报告 COVID-19 的一种罕见表现和视网膜多发性一过性白点综合征(MEWDS)。2021 年 4 月,一名 40 岁女性患者因急性视力障碍入住黑山临床中心眼科(波德戈里察,黑山)。患者的主要主诉是 COVID-19 感染后 14 天出现突发性视力下降。进行了全面的眼部检查,随后进行了眼底检查、光学相干断层扫描(OCT)和荧光素血管造影(FA)检查。结果显示与 MEWDS 相关的视网膜变化。患者进行了额外的检查以排除多发性视网膜炎的常见原因,所有检查均无明显异常。因此,结论是视网膜炎是 COVID-19 的并发症。鉴于其非侵入性,眼底检查应作为 COVID-19 患者视网膜变化的标准筛查方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5c/9843462/158da898db07/IJMS-48-98-g001.jpg

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