Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, CDC.
MMWR Morb Mortal Wkly Rep. 2019 Nov 8;68(44):993-998. doi: 10.15585/mmwr.mm6844a1.
Lung and bronchus (lung) cancer is the leading cause of cancer death in the United States (1). In 2016, 148,869 lung cancer deaths were reported.* Most lung cancers can be attributed to modifiable exposures, such as tobacco use, secondhand smoke, radon, and asbestos (1). Exposure to lung cancer risk factors vary over time and by characteristics such as sex, age, and nonmetropolitan or metropolitan residence that might affect lung cancer rates (1,2). A recent report found that lung cancer incidence rates were higher and decreased more slowly in nonmetropolitan counties than in metropolitan counties (3). To examine whether lung cancer incidence trends among nonmetropolitan and metropolitan counties differed by age and sex, CDC analyzed data from U.S. Cancer Statistics during 2007-2016, the most recent years for which data are available. During the 10-year study period, lung cancer incidence rates were stable among females aged <35, 45-64, and ≥75 years in nonmetropolitan counties, were stable among females aged <35 years in metropolitan counties, and decreased in all other groups. Overall, among males, lung cancer incidence rates decreased from 99 to 82 per 100,000 in nonmetropolitan areas and from 83 to 63 in metropolitan areas; among females, lung cancer incidence rates decreased from 61 to 58 in nonmetropolitan areas and from 57 to 50 in metropolitan areas. A comprehensive approach to lung cancer prevention and control includes such population-based strategies as screening for tobacco dependence, promoting tobacco cessation, implementing comprehensive smoke-free laws, testing all homes for radon and using proven methods to lower high radon levels, and reducing exposure to lung carcinogens such as asbestos (1). Increasing the implementation of these strategies, particularly among persons living in nonmetropolitan counties, might help to reduce disparities in the decline of lung cancer incidence.
肺和支气管(肺部)癌是美国癌症死亡的主要原因(1)。2016 年,报告了 148,869 例肺癌死亡病例*。大多数肺癌可归因于可改变的暴露因素,例如吸烟、二手烟、氡和石棉(1)。随着时间的推移,人们接触肺癌风险因素的情况会发生变化,且会受到性别、年龄以及非城市或城市居住等特征的影响,这些特征可能会影响肺癌的发病率(1,2)。最近的一份报告发现,与城市县相比,非城市县的肺癌发病率更高,且下降速度更慢(3)。为了研究非城市县和城市县的肺癌发病率趋势是否因年龄和性别而有所不同,疾病预防控制中心分析了美国癌症统计数据,数据来源于 2007 年至 2016 年,这是可用数据的最近年份。在这项为期 10 年的研究期间,非城市县 <35 岁、45-64 岁和≥75 岁女性的肺癌发病率保持稳定,城市县 <35 岁女性的肺癌发病率保持稳定,其他年龄段的女性发病率则有所下降。总体而言,男性肺癌发病率从非城市地区的 99 例/10 万人降至 82 例/10 万人,城市地区从 83 例/10 万人降至 63 例/10 万人;女性肺癌发病率从非城市地区的 61 例/10 万人降至 58 例/10 万人,城市地区从 57 例/10 万人降至 50 例/10 万人。综合的肺癌预防和控制方法包括针对烟草依赖的筛查、促进戒烟、实施全面的无烟法律、对所有房屋进行氡测试并使用已证实的方法降低氡的高浓度、减少接触石棉等肺癌致癌物(1)。特别是在非城市县,增加这些策略的实施,可能有助于减少肺癌发病率下降方面的差异。