Hallberg L, Bengtsson C, Garby L, Lennartsson J, Rossander L, Tibblin E
Bull World Health Organ. 1979;57(6):947-54.
The prevalence of iron deficiency anaemia among Swedish women of child-bearing age has fallen markedly since the mid-1960s. At that time, population studies in Göteborg and Uppsala showed that iron deficiency anaemia was present in about 25-30% of women. Later, in population studies in Göteborg in 1968-69 and 1974-75, the prevalence in the same age group was found to have fallen to 6-7%. Several factors may explain the improved iron status. The level of iron fortification of flour was increased from 30 mg/kg of flour in 1943 to 65 mg in 1970, this increase adjusting the iron intake to compensate for the lower energy requirement and expenditure of present-day living habits. There has also been a marked increase in the intake of iron tablets and of tablets containing ascorbic acid.An analysis of various factors indicates that the 20-25% improvement in iron status can be accounted for by increased use of oral contraceptives (3-4%), the impact of increased iron fortification (7-8%), the widespread use of ascorbic acid supplements (3%), and greater prescribing of iron tablets (10%).This analysis of the factors leading to the marked reduction in the prevalence of iron deficiency anaemia among Swedish women may be useful to public health planners in other countries with similar problems. Our results indicate that several factors need to be considered when planning controlled field trials and evaluating the results obtained. The methods used to analyse the impact of different factors on the reduction in iron deficiency can also be used to predict the effects of various public health measures on the iron status of a population.
自20世纪60年代中期以来,瑞典育龄妇女缺铁性贫血的患病率显著下降。当时,哥德堡和乌普萨拉的人口研究表明,约25%-30%的女性存在缺铁性贫血。后来,在1968-1969年和1974-1975年对哥德堡的人口研究中,发现同一年龄组的患病率已降至6%-7%。有几个因素可以解释铁状况的改善。面粉的铁强化水平从1943年的每千克面粉30毫克提高到1970年的65毫克,这一增加调整了铁摄入量,以弥补当今生活习惯中较低的能量需求和消耗。铁剂和含抗坏血酸片剂的摄入量也显著增加。对各种因素的分析表明,铁状况20%-25%的改善可归因于口服避孕药使用增加(3%-4%)、铁强化增加的影响(7%-8%)、抗坏血酸补充剂的广泛使用(3%)以及铁剂处方增加(10%)。对导致瑞典女性缺铁性贫血患病率显著降低的因素进行的这种分析,可能对其他存在类似问题的国家的公共卫生规划者有用。我们的结果表明,在规划对照现场试验和评估所获结果时需要考虑几个因素。用于分析不同因素对缺铁减少影响的方法,也可用于预测各种公共卫生措施对人群铁状况的影响。