Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Av. Universidad km 1. Ex Hacienda de Aquetzalpa. Tulancingo, Hidalgo 43600, Mexico.
Universidad Autónoma del Estado de Hidalgo, Escuela Superior de Apan, Carretera Apan-Calpulalpan s/n, Colonia, Chimalpa Tlalayote, Apan, Hidalgo 43920 Mexico.
Molecules. 2019 Nov 7;24(22):4031. doi: 10.3390/molecules24224031.
Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3-6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC can be extracted from different sources such as bovine or porcine. These sources have presented health limitations in the last years. Recently research has shown good properties of the HC found in skin, scale, and bones from marine sources. Type and source of extraction are the main factors that affect HC properties, such as molecular weight of the peptide chain, solubility, and functional activity. HC is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. The present review presents the different types of HC, sources of extraction, and their applications as a biomaterial.
水解胶原蛋白（HC）是一组具有低分子量（3-6 kDa）的肽，可以通过在特定孵育温度的酸性或碱性介质中的酶促作用获得。HC 可以从不同的来源中提取，例如牛或猪。这些来源在过去几年中出现了健康方面的限制。最近的研究表明，来自海洋来源的皮肤、鳞片和骨骼中的 HC 具有良好的特性。类型和提取来源是影响 HC 特性的主要因素，例如肽链的分子量、溶解度和功能活性。HC 广泛应用于食品、制药、化妆品、生物医学和制革等多个行业。本综述介绍了不同类型的 HC、提取来源及其作为生物材料的应用。
