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原发性水痘-带状疱疹病毒感染后的短暂性缄默症、病理性发笑和小脑共济失调。

Transient mutism, pathological laughter and cerebellar ataxia after primary varicella-zoster virus infection.

作者信息

Brito Teresa, Oliveira Inês, Silva Laurinda, Parente Susana

机构信息

Pediatrics Department, Hospital de São Bernardo, Setubal, Portugal.

Pediatrics Department, Hospital de São Bernardo, Setubal, Portugal

出版信息

BMJ Case Rep. 2019 Nov 7;12(11):e230683. doi: 10.1136/bcr-2019-230683.

DOI:10.1136/bcr-2019-230683
PMID:31704797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6855846/
Abstract

Acute postinfectious cerebellitis is characterised by inflammatory involvement of the cerebellum and consequent cerebellar dysfunction, usually presenting a benign and self-limited course. Common symptoms described in the literature include ataxia, peripheral facial paralysis, aphasia, spinal dysfunction and eventually hydrocephalus. We describe a rare presentation of acute cerebellitis after varicella, in a 6-year-old child, who presented with ataxia, dysmetria, mutism and pathological laughter.

摘要

急性感染后小脑炎的特征是小脑出现炎症并随之导致小脑功能障碍,通常呈良性且自限性病程。文献中描述的常见症状包括共济失调、周围性面瘫、失语、脊髓功能障碍,最终可出现脑积水。我们报告一名6岁儿童在水痘感染后出现急性小脑炎的罕见病例,该患儿表现为共济失调、辨距不良、缄默症和病理性哭笑。

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1
Transient mutism, pathological laughter and cerebellar ataxia after primary varicella-zoster virus infection.原发性水痘-带状疱疹病毒感染后的短暂性缄默症、病理性发笑和小脑共济失调。
BMJ Case Rep. 2019 Nov 7;12(11):e230683. doi: 10.1136/bcr-2019-230683.
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Acute cerebellar ataxia during acute COVID-19: A case series and review of the literature.急性 COVID-19 期间的急性小脑共济失调:病例系列及文献复习。
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本文引用的文献

1
[Acute cerebellitis in children: regarding different etiologies].[儿童急性小脑炎:关于不同病因]
Acta Med Port. 2012;25 Suppl 1:38-41. Epub 2012 Nov 2.
2
Transient mutism and pathologic laughter in the course of cerebellitis.
Pediatr Neurol. 2009 Jul;41(1):49-52. doi: 10.1016/j.pediatrneurol.2009.01.013.
3
Transient cerebellar mutism in the course of acute cerebellitis.急性小脑炎病程中的短暂性小脑缄默症
Pediatr Neurol. 2004 Jan;30(1):71-4. doi: 10.1016/s0887-8994(03)00420-x.
4
Reversible cerebral perfusion alterations in children with transient mutism after posterior fossa surgery.后颅窝手术后短暂性缄默症患儿的可逆性脑灌注改变
Childs Nerv Syst. 1998 Mar;14(3):114-9. doi: 10.1007/s003810050191.