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一名免疫功能正常儿童因原发性水痘感染导致的小脑缄默症。

Cerebellar mutism caused by primary varicella infection in an immunocompetent child.

作者信息

Erol Ilknur, Özkale Yasemin, Saygi Semra, Alehan Füsun

机构信息

Division of Child Neurology, Baskent University Faculty of Medicine, Adana, Turkey.

Department of Pediatrics, Baskent University Faculty of Medicine, Adana, Turkey

出版信息

J Child Neurol. 2014 Jun;29(6):830-2. doi: 10.1177/0883073813477202. Epub 2013 Feb 26.

Abstract

Varicella (chickenpox) is a common childhood infection caused by the varicella-zoster virus, which is often self-limiting and usually benign. Although uncommon, neurologic complications of varicella have been documented that include postinfectious cerebellar ataxia, meningoencephalitis, Reye syndrome, myelitis, optic neuritis, stroke, Guillain-Barré syndrome, seventh cranial nerve palsy, and Ramsay-Hunt syndrome. In this case study, the authors describe a 7-year-old girl who presented with varicella skin rash with unsteady gait and anarthria on day 2, and her condition was attributed to cerebellar mutism. To date, this complication has never been reported in a child with primary varicella infection. Therefore, this case study documents a rare but serious complication of childhood chickenpox.

摘要

水痘是由水痘-带状疱疹病毒引起的一种常见的儿童感染性疾病,通常具有自限性且一般为良性。尽管不常见,但水痘的神经系统并发症已有文献记载,包括感染后小脑性共济失调、脑膜脑炎、瑞氏综合征、脊髓炎、视神经炎、中风、吉兰-巴雷综合征、第七颅神经麻痹和拉姆齐-亨特综合征。在本病例研究中,作者描述了一名7岁女孩,她在出疹第2天出现水痘皮疹,并伴有步态不稳和构音障碍,其病情被归因于小脑缄默症。迄今为止,这种并发症从未在原发性水痘感染的儿童中报道过。因此,本病例研究记录了儿童水痘一种罕见但严重的并发症。

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