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大麻与健康研究:快速进展需要创新的研究设计。

Cannabis and Health Research: Rapid Progress Requires Innovative Research Designs.

机构信息

Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.

Institute of Cognitive Science, University of Colorado Boulder, Boulder, CO, USA.

出版信息

Value Health. 2019 Nov;22(11):1289-1294. doi: 10.1016/j.jval.2019.05.005. Epub 2019 Oct 18.

DOI:10.1016/j.jval.2019.05.005
PMID:31708066
Abstract

The United States has witnessed enormous changes concerning the acceptance of medicinal and recreational cannabis use. Sixty-three percent of the US population has access to medicinal cannabis markets, which offer increasingly diverse and potent cannabis products. Considering the rapidly changing cultural, political, and legal landscape, the scientific literature does not adequately inform public policy, medical decision making, or harm reduction approaches. The goals of this paper are to (1) investigate the state of cannabis research on medical conditions commonly treated with cannabis, (2) review the barriers that have led to large gaps between cannabis use and available empirical data, and (3) suggest a path forward with new research designs to address these gaps. Thus, we aim to advance a more nuanced understanding of the barriers to cannabis research and suggest innovative research designs necessary for rapid development of a meaningful knowledge base.

摘要

美国在接受药用和娱乐用大麻使用方面发生了巨大变化。63%的美国人可以进入药用大麻市场,这些市场提供越来越多样化和有效的大麻产品。考虑到文化、政治和法律环境的快速变化,科学文献不能充分为公共政策、医疗决策或减少伤害方法提供信息。本文的目的是:(1)调查针对常用大麻治疗的医疗条件的大麻研究状况;(2)审查导致大麻使用和现有经验数据之间存在巨大差距的障碍;(3)提出新的研究设计,以解决这些差距。因此,我们旨在更深入地了解大麻研究的障碍,并提出必要的创新研究设计,以快速建立有意义的知识库。

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The Changing Drug Culture: Medical and Recreational Marijuana.不断变化的毒品文化:医用大麻与消遣用大麻
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Med Cannabis Cannabinoids. 2024 Dec 10;7(1):257-267. doi: 10.1159/000542550. eCollection 2024 Jan-Dec.
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The Interplay of Exogenous Cannabinoid Use on Anandamide and 2-Arachidonoylglycerol in Anxiety: Results from a Quasi-Experimental Ad Libitum Study.
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