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特应性皮炎与食物过敏的关系。

Relationship Between Atopic Dermatitis and Food Allergy.

机构信息

Department of Allergy and Clinical Immunology, Hospital Sant Joan de Déu, Barcelona, Spain.

出版信息

Curr Pediatr Rev. 2020;16(2):115-122. doi: 10.2174/1573396315666191111122436.

Abstract

Consistent evidence has been found on the relationship between food allergy (FA) and atopic dermatitis (AD) in some children. Food sensitization can be often found in these patients. Allergy should be confirmed, though, with a food challenge test (FC) before advising a restrictive diet which could be harmful for the patient. Younger children with AD frequently show sensitization to egg, milk or peanut, while older ones and adults are more often sensitized to environmental allergens such as house dust mites, moulds, animal dander or pollens. It is well known that a barrier disturbance plays a main role in the development of sensitization and allergy. Therefore, due to the early appearance of AD, preventive newborn skincare with emollients and early introduction of food appear to be very important to determine food tolerance.

摘要

已经有充分的证据表明食物过敏(FA)和特应性皮炎(AD)在一些儿童中存在关联。这些患者通常会出现食物致敏现象。然而,在建议采用可能对患者有害的饮食限制之前,应该通过食物挑战试验(FC)来确认过敏。患有 AD 的幼儿通常对鸡蛋、牛奶或花生过敏,而年龄较大的儿童和成年人则更容易对环境过敏原如尘螨、霉菌、动物皮屑或花粉过敏。众所周知,屏障功能障碍在致敏和过敏的发展中起着主要作用。因此,由于 AD 早期出现,对新生儿进行保湿护肤品预防和早期引入食物可能对确定食物耐受性非常重要。

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