Department of Veterinary Public Health & Preventive Medicine, University of Ibadan, Ibadan, Center for Control and Prevention of Zoonoses, University of Ibadan, Ibadan, Nigeria.
Department of Veterinary Public Health & Preventive Medicine, University of Ibadan, Ibadan.
Int J Tuberc Lung Dis. 2019 Nov 1;23(11):1162-1170. doi: 10.5588/ijtld.18.0641.
Zoonotic transmission of mycobacteria between humans and other animal species is an important aspect of the epidemiology of tuberculosis (TB) in regions of the world where the burden of the disease in humans and other animals is high. This is particularly important in areas in which sociocultural factors increase the possibility for interspecies transmission of different mycobacteria. Carrying out a review of the published literature involving laboratory-confirmed TB cases (by culture) and/or biochemical and molecular identification, we described the presence of and infections in humans and animals from 1975 to 2014. Overall, 1693 isolates of complex and other mycobacteria were identified and reported, of which 1131 represented , 286 represented , 71 represented , and 205 represented other mycobacteria. Importantly, 1.3% (15/1131) of the isolates reported were identified in cattle, while 8.0% (23/286) of the isolates reported were isolated from humans. We suggest that representative sampling of TB cases in both hosts, studied by molecular identification tools, will help significantly in deciphering ongoing transmission between animals and humans in both directions and will enhance TB control in Nigeria.
人兽之间分枝杆菌的动物源性传播是世界范围内人兽结核病(TB)流行的一个重要方面,这些地区的人兽 TB 负担较重。在那些由于社会文化因素而增加了不同分枝杆菌种间传播可能性的地区,这一点尤为重要。我们对 1975 年至 2014 年已发表文献中涉及实验室确诊(通过培养)和/或生物化学和分子鉴定的 TB 病例进行了综述,描述了人类和动物中 复合群分枝杆菌和 复合群分枝杆菌的存在情况。总共鉴定和报告了 1693 株 复合群分枝杆菌和其他分枝杆菌,其中 1131 株代表 ,286 株代表 ,71 株代表 ,205 株代表其他分枝杆菌。重要的是,报告的 1131 株 分离株中有 1.3%(15/1131)是从牛中分离出来的,而报告的 286 株 分离株中有 8.0%(23/286)是从人身上分离出来的。我们建议,对宿主中 TB 病例进行代表性抽样,并采用分子鉴定工具进行研究,将有助于深入了解动物和人类之间双向的持续传播情况,并加强尼日利亚的结核病控制工作。